Moderately hyperglycemia as an independent prognostic factor for the worse outcome of COVID-19 |
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| Affiliation: | 1. Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran;2. Department of Medical Biotechnology, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran;3. Respiratory Department, School of Medicine, Tehran University of Medical Science, Tehran, Iran;4. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran |
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| Abstract: | BackgroundBlood sugar (BS) has been proposed as a prognostic factor for COVID-19. In this historical cohort study we evaluated the association between admission time BS and COVID-19 outcome.MethodsFirst, hospitalized COVID-19 patients were divided into three groups; Non-diabetic patients with BS < 140 mg/dl (N = 394), non-diabetic patients with BS ≥ 140 mg/dl (N = 113) and diabetic patients (N = 315). Mortality, ICU admission, and length of hospital stay were compared between groups and odds ratio was adjusted using logistic regression.ResultsAfter adjustment with pre-existing conditions and drugs, it was shown that non-diabetic patients with BS ≥ 140 mg/dl are at increased risk of mortality (aOR 1.89 (0.99–3.57)) and ICU admission (aOR 2.62 (1.49–4.59)) even more than diabetic patients (aOR 1.72 (1.07–2.78) for mortality and aOR 2.28 (1.47–3.54) for ICU admission.ConclusionsAdmission time hyperglycemia predicts worse outcome of COVID-19 and BS ≥ 140 mg/dl is associated with a markedly increase in ICU admission and mortality. |
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| Keywords: | COVID-19 Blood Sugar Hyperglycemia Diabetes Mortality |
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