The Tiniest Babies Registry: A registry of survivors born weighing less than 400 grams |
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| Affiliation: | 1. Department of Biomedical Engineering, Widener University, Chester, PA, 19013, USA;2. Neonatology Research Laboratory, Department of Pediatrics, The Children''s Regional Hospital at Cooper, Cooper Medical School of Rowan University, Suite Dorrance 755, One Cooper Plaza, Camden, NJ, 08103, USA;1. Division of Neonatology and Pulmonary Biology, Perinatal Institute, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;2. Department of Pediatrics, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;3. Center for Lung Regenerative Medicine, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;4. Division of Developmental Biology, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;1. Bayer Pharma U.S LLC, 100 Bayer Boulevard, Whippany, NJ, NJ 07981, USA;2. International Neonatal Consortium, USA;3. Tufts Medical Center and the Tufts Clinical and Translational Science Institute, Boston, MA, USA |
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| Abstract: | The Tiniest Babies Registry was launched in the year 2000 as a web-based registry for patients who survived to discharge after being born with birth weights below 400 grams. The registry began with 15 patients and by January 2022 had grown to 291, ranging in birth weight from 212 to 399 grams and in gestational age from 21 to 34 weeks. Three patients were born in the 1930s, and no others were born until 1985. The greatest number in a single year was 21 in 2010. The infants were born in 16 countries, but 166 of 291 (57%) were born in the U.S. All except 10 of the infants were small for gestational age at birth. No systematic data on the long-term outcomes of these patients is available, but the information submitted by selected registry participants indicates they are at increased risk for continued delays in growth and development. |
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| Keywords: | Tiniest babies <400 grams Micropremies Extremely low birth weight Small for gestational age Intrauterine growth restriction |
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