| 涎腺腺样囊性癌神经内分泌性探讨 |
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| 引用本文： | 孙长伏,钟鸣,王兆元,王玉新. 涎腺腺样囊性癌神经内分泌性探讨[J]. 华西口腔医学杂志, 1999, 17(2): 0-127,I006 |
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| 作者姓名： | 孙长伏 钟鸣 王兆元 王玉新 |
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| 作者单位： | 中国医科大学第一临床学院口腔颌面外科 |
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| 摘 要： | 目的 探讨涎腺腺样囊性癌具有神经内分泌性的可能性，方法 采用神经内分泌细胞及肿瘤细胞所特有及相关的抗体Ｓ－１００蛋白，神经特异性烯醇酶，嗜铬素Ａ和突触素４种标记物对其在该肿瘤的表达进行免疫组织化学研究。结果 ５０例涎腺腺样囊癌中Ｓ－１００蛋白阳性表达４２例（８４％）神经特异性烯醇酶阳性表达３２例（６４％）。嗜铬素Ａ阳性表达８例（１６％），突触素阳性表达７例（１４％），结论：涎腺腺样囊性癌部分细胞具
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| 关 键 词： | 涎腺腺样囊性癌 神经内分泌 |
| 收稿时间： | 1999-04-25 |
| 修稿时间： | 1999-04-25 |
Detection of Neuroendocrine Feature about Salivary Adenoid Cystic Carcinoma |
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| Sun Changfu,Zhong Ming,Wang Zhaoyuan,Wang Yuxin. Detection of Neuroendocrine Feature about Salivary Adenoid Cystic Carcinoma[J]. West China journal of stomatology, 1999, 17(2): 0-127,I006 |
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| Authors: | Sun Changfu Zhong Ming Wang Zhaoyuan Wang Yuxin |
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| Affiliation: | Department of Oral and Maxillofacial Surgery, First Clinical Medical College, China Medical University. |
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| Abstract: | Objective: To study the possibility of neuroendocrine feature of salivary adenoid cystic carcinoma (SACC).Methods: Immunohistochemical staining was operated in SACC with S 100 protein, Neuron specific enolase (NSE), chromogranin A and synaptophysin which are specific and correlative with neuroendocrine and neoplasias.Results: The positive expression of S 100, NSE, chromogranin and synaptophysin were respectively 42, 32, 8 and 7 in 50 cases of SACC.Conclusion: There is possibility of neuroendocrine feature in some SACC cells. |
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| Keywords: | salivary adenoid cystic carcinoma neuroendocrine |
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