| 国产依丽黄酮抗去势大鼠骨质疏松的实验研究 |
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| 引用本文： | 欧阳秋明,李洪洋,郑志仁,翁玲玲. 国产依丽黄酮抗去势大鼠骨质疏松的实验研究[J]. 四川大学学报(医学版), 1994, 0(2) |
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| 作者姓名： | 欧阳秋明 李洪洋 郑志仁 翁玲玲 |
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| 作者单位： | 公共卫生学院病理学教研室，药学院，四川省卫生防疫站 |
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| 摘 要： | 切除３月龄雌性大鼠双侧卵巢后，口服国产依丽黄酮１２周，与单纯卵巢切除组对照，用骨计量学等方法对国产依丽黄酮药效及剂量反应关系进行综合评价。结果显示：切除卵巢后骨量显著减少，骨无机质含量降低，破骨及成骨活性均增加，但破骨大于成骨；口服依丽黄酮后，各剂量组恢复至接近正常水平。由此表明，国产依丽黄酮能有效防止切除卵巢后大鼠的失骨
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| 关 键 词： | 骨质疏松，卵巢切除，国产依丽黄酮，骨计量学 |
Experimental study on the Effect of Ipriflavone Against Osteoporosis in Ovariectomized Rats |
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| Ouyang Qiuming, Li Hongyang, Zheng Zhiren, Weng Lingling. Experimental study on the Effect of Ipriflavone Against Osteoporosis in Ovariectomized Rats[J]. Journal of Sichuan University. Medical science edition, 1994, 0(2) |
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| Authors: | Ouyang Qiuming Li Hongyang Zheng Zhiren Weng Lingling |
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| Affiliation: | Ouyang Qiuming, Li Hongyang, Zheng Zhiren, Weng Lingling1.Department of Pathology,School of Public Health,2.School of Pharmacy |
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| Abstract: | |
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| Keywords: | Osteoporosis Ovariectomized rats Ipriflavone Bone histomorphometry |
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