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Dioscorea villosa (wild yam) induces chronic kidney injury via pro-fibrotic pathways |
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| Authors: | Ken Wojcikowski Hans Wohlmuth David W Johnson Glenda Gobe |
| Affiliation: | Molecular and Cellular Pathology, School of Medicine, University of Queensland, Brisbane, Queensland, Australia; Department of Natural and Complementary Medicine, Southern Cross University, Military Road, Lismore, NSW 2480, Australia. |
| Abstract: | |
| Keywords: | AA, aristolochic acid AAN, aristolochic acid nephropathy α-SMA, alpha smooth muscle actin CKD, chronic kidney disease CTGF, connective tissue growth factor EMT, epithelial-to-mesenchymal transdifferentiation HO-1, heme oxygenase-1 IHC, immunohistochemistry IL, interleukin NFκB, nuclear factor κB TBST, Tris-buffered saline and 0.05% Tween20 TGFß1, transforming growth factor-ß1 TNF-α, tumor necrosis factor alpha |
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