Laser flow cytofluorometry as a supplementary method of determining the degree of tumor differentiation in breast cancer patients

Content of cell DNA and RNA was studied by method of laser flowing cytophotometry in 21 cases of pretumorous conditions and 64 tumours of mammary gland. A clear-cut difference in DNA and RNA histograms is shown in non-proliferative and proliferative forms of mastopathy, in mastopathy and infiltrating mammary gland carcinoma. Likewise, a clear-cut correlation between the degree of malignancy and a nucleic acid content in the carcinoma cells is established.