| 11C-乙酸盐在肿瘤PET或PET-CT中的应用 |
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| 引用本文： | 马文超,徐文贵. 11C-乙酸盐在肿瘤PET或PET-CT中的应用[J]. 国际放射医学核医学杂志, 2011, 35(1): 23-27. DOI: 10.3760/cma.j.issn.1673-4114.2011.01.007 |
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| 作者姓名： | 马文超 徐文贵 |
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| 作者单位： | 天津医科大学附属肿瘤医院分子影像及核医学诊疗科,300060 |
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| 基金项目： | 天津市自然科学基金重点项目，天津市高等学校科技发展基金 |
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| 摘 要： | 18F-FDG是临床上应用最多、范围最广的正电子显像剂,但其对于某些肿瘤的诊断缺乏敏感性和特异性.11C-乙酸盐与18F-FDG相比,有不同的体内分布方式及细胞摄取机制,是近年来众多研究证实很有希望在某些方面弥补 18F-FDG显像不足的正电子显像剂.该文综述了目前11C-乙酸盐PET或PET-CT的机制、研究领域及最...
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| 关 键 词： | 乙酸盐类 碳放射性同位素 肿瘤 正电子发射断层显像术 体层计算机,X线计算机 |
The application o 11C-acetate PET or PET-CT for tumors |
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| MA Wen-chao,XU Wen-gui. The application o 11C-acetate PET or PET-CT for tumors[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2011, 35(1): 23-27. DOI: 10.3760/cma.j.issn.1673-4114.2011.01.007 |
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| Authors: | MA Wen-chao XU Wen-gui |
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| Abstract: | 18F-FDG is generally used for tumors'PET,and it is the most and widest useful positron radiopharmaceutical in the clinic.But it does not have enough sensitivity and specificity for some kinds of tumors.11C-acetate has different distribution in body and uptaken mechanism by cell from 18F-FDG.Many studies have confirmed that 11C-acetate has the potential value to make up the insufficiency of 18F-FDG.The researches on 11C-acetate PET or PET-CT are reviewed in this paper,including the mechanism,research area and the newest progress. |
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| Keywords: | Acetates Carbon radioisotopes Neoplasms Positron-emssion tomography Tomography,X-ray computed |
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