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Ox-LDL和C-反应蛋白与子痫前期严重性的相关性研究
引用本文:王立俊,张立功,左嫦婷. Ox-LDL和C-反应蛋白与子痫前期严重性的相关性研究[J]. 中国现代医学杂志, 2008, 18(24): 3573-3576
作者姓名:王立俊  张立功  左嫦婷
作者单位:山东大学附属省立医院,山东,济南,250021
摘    要:目的 探讨子痫前期血浆氧化低密度脂蛋白(ox-LDL)和C-反应蛋白(CRP)的水平与子痫前期严重性的相关性.方法 26例正常晚期妊娠妇女,32例轻度子痫前期妇女,26例重度子痫前期晚孕妇女.以MAP作为疾病严重性的指标,测定血浆ox-LDL和CRP水平,与MAP行相关性分析.结果 血浆CRP及ox-LDL水平在轻度和重度子痛前期组明显高于正常晚孕组;子痫前期组MAP和CRP(r=0.264,P=0.023).MAP和ox-LDL(r=0.256,P=0.0275)之间存在明显的相关性.结论 子痫前期时ox-LDL和CRP水平升高,与疾病的严重程度存在正相关性.

关 键 词:子痫前期  C-反应蛋白  氧化低密度脂蛋白

Relationship of ox-LDL and C-reactive protein with severity of preeclampsia
WANG Li-jun , ZHANG Li-gong , ZUO Chang-ting. Relationship of ox-LDL and C-reactive protein with severity of preeclampsia[J]. China Journal of Modern Medicine, 2008, 18(24): 3573-3576
Authors:WANG Li-jun    ZHANG Li-gong    ZUO Chang-ting
Affiliation:WANG Li-jun,ZHANG Li-gong,ZUO Chang-ting(Sh,ong Provincial Hospital Affiliated to Sh,ong University,Jinan,Sh,ong 250021,P.R.China)
Abstract:[Objective] To determine the levels of plasma oxidized low density lipoprotein(ox-LDL) and C-reactive protein(CRP) in preeclampsia and their association with the severity of the disease.[Methods] CRP and plasma levels of ox-LDL were investigated and statistical analysis in 26 cases of normal pregnant women,32 cases with mild preeclampsia and 26 cases with severe preeclampsia in the third trimester of pregnancy.Mean arterial pressure(MAP) was used as an indicator of the severity of the disease.[Results] CRP ...
Keywords:preeclampsia  C-reactive protein  oxidized low-density lipoproteins  
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