支气管动脉灌注化疗联合全身静脉化疗治疗中晚期肺癌的疗效观察

目的 研究支气管动脉灌注化疗联合全身化疗治疗中晚期非小细胞肺癌的临床价值。方法 138例中晚期肺癌患者分为两组:A组:介入化疗的同时联合全身静脉化疗;B组:单纯全身静脉化疗。两组全身化疗方案相同。对其临床资料进行回顾性分析。结果 A组近期有效率、半年生存率、年生存率和疾病进展时间分别为61.42%、94.29%、72.86%和85.94天,B组分别为46.27%、82.35%、42.65%和125.23天。两组均有显著性差异。结论 中晚期非小细胞肺癌行介入治疗联合全身化疗可明显提高疗效,延长生存期并改善生存质量。

Curative effect of chemotherapy on advanced non-small cell lung cancer by bronchial artery infusion plus systemic chemotherapy

Object To study the clinical effect of bronchial artery infusion （BAI）chemotherapy combined with systemic chemotherapy for patient with advanced non - small cell lung cancer. Methods 138 cases with advanced non - small cell lung cancer were divided into two groups. 70 cases（ A group） received BAI chemotherapy conbimed with systemic chemotherapy. 68 cases （ B group） were treated with systemic chemotherapy alone. The same systemic chemotherapy was taken in the two groups. The clinical data were analyzed retrospectively. Resuits Short - term response rate （ 61.42% ） , time to progression （TTP） （ 125.23 days ） , half - year survival rate （94.29%）and 1 -year survival rate（94.29% ）in BAI chemotherapy group were significantly higher than those in control group（46.27% ,85.94 days,82.35% ,42.65% respectively）. Conclusion BAI chemotherapy combined with systemic chemotherapy is helpful for patient with advanced non - small cell lung cancer to improve therapeutic effect, to prolong survival time and improve quality of life.