节细胞神经瘤的CT、MRI表现与病理对照分析

目的 分析节细胞神经瘤的CT与MRI表现以及与病理的对照.方法 回顾性分析经手术病理证实的11例节细胞神经瘤的CT与MRI表现及临床病理资料,11例全部行CT检查,其中4例同时行MRI检查.结果 11例节细胞神经瘤大小范围在3cm×4cm×4cm～6cm×7.8cm× 8.5cm之间.肿瘤形态表现为边界清楚的椭圆形肿块,亦可呈不规则形,沿冠状轴生长,可对邻近大血管包绕1/2以上.CT平扫表现为水样至肌肉样密度,多表现低密度,其内散在点状或结节状钙化,不增强或轻度增强居多.MRI T1WI为低信号,T2WI为不均匀混杂信号,但以高信号为主;动态增强扫描中,肿瘤早期不强化,并呈逐渐强化的特征,肿瘤包膜可强化.结论 节细胞神经瘤的CT与MRI表现有一定特征性,并与病理中肿瘤富含大量黏液基质呈相关性.

CT and MRI appearances of ganglioneuroma with pathologic correlation

Objective The purpose of this study was to evaluate the CT and MR findings of ganglioneuroma and to correlate imaging and histologie features. Methods CT or MRI examinations were performed in eleven cases of ganglioneuroma being pathologically confirmed. Results In llpatients with ganglioneuroma, the mass ranged in size from 3 cruX4 cruX4 cm to 6 crux 7.8 crux 8.5 cm. Ganglioneuromas appeared as the well defined, oval or irregular masses along coronal axle, partial or complete surrounding of one or more major blood vessels with little or no luminal narrowing. CT attenuation of tumors was like that of water to muscle and predominantly low. There was punctuate or tubercle calcification in tumors and no enhancement or slight enhancement on contrast-enhanced CT. MRI signals were mainly low intensity on T1WI and inhomogeneously high intensity on T2 WI. Dynamic enhancement studies showed a lack of early enhancement but gradual increasing. The capsule of tumor might may be enhanced. Conclusion The manifestiongs of ganglioneuroma on CT and MRI have some characteristics, which might correlate with abundant histological myxoid matrix.