| 电子垃圾拆解集散地居民铅、镉、铜内暴露水平与淋巴细胞双微核率的关系 |
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| 引用本文： | 陈兰,徐国建,张裕曾,居颖,石吉彬,江琦,李丽萍,袁晶,邬堂春,陈学敏.电子垃圾拆解集散地居民铅、镉、铜内暴露水平与淋巴细胞双微核率的关系[J].劳动医学,2008,25(5):442-445. |
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| 作者姓名： | 陈兰 徐国建 张裕曾 居颖 石吉彬 江琦 李丽萍 袁晶 邬堂春 陈学敏 |
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| 作者单位： | 华中科技大学同济医学院公共卫生学院劳动卫生与环境卫生学系;华中科技大学同济医学院公共卫生学院环境与健康教育部重点实验室;汕头大学医学院伤害预防研究中心; |
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| 摘 要： | 目的]研究电子垃圾拆解集散地居民血尿铅、镉、铜的暴露水平和淋巴细胞双微核率的变化及其影响因素。方法]选择某电子垃圾拆解集散地居民58人为暴露组（男性44人，女性14人），平均年龄为33．0岁；距离集散地50km，且无明显工业污染的农业区人群80人为对照组（男性41名，女性39名），平均年龄为43．7岁。采用石墨炉原子吸收光谱法检测血铅、血镉和尿铅、尿镉、尿铜含量，火焰原子吸收光谱法测定血清铜含量；胞质阻滞双微核实验测定淋巴细胞双微核率。结果]暴露组居民血铅和尿铜中位数分别为0．52μmol／L和51．97μmol／mmol肌酐，均高于对照组（P〈0．05）。暴露组人群双微核率中位数（4‰）是对照组（1‰）的4倍，年龄是血镉增高的危险因素（OR=1．1，P〈0．01）；电子垃圾拆解职业暴露史是影响血铅水平及双微核率的危险因素（OR=2．9，P〈0．05；OR=6．7，P〈0．01）。结论]电子垃圾拆解地居民血铅、尿铜水平及淋巴细胞双微核率均高于对照区居民。
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| 关 键 词： | 电子垃圾 血铅 血镉 血清铜 尿铅 尿镉 尿铜 双微核率 |
LeveLs of Lead,Cadmium,Copper in Blood and Urine and Frequencies of Micronucleated Binucleated Cells among Residents in an Electronic Waste Recycling Site in China |
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| CHEN Lan XU Guo-jian ZHANG Yu-zeng JU Yin SHI Ji-bin JIANG Qi LI Li-ping YUAN Jing WU Tang-chun CHEN Xue-min.LeveLs of Lead,Cadmium,Copper in Blood and Urine and Frequencies of Micronucleated Binucleated Cells among Residents in an Electronic Waste Recycling Site in China[J].Journal of Labour Medicine,2008,25(5):442-445. |
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| Authors: | CHEN Lan XU Guo-jian ZHANG Yu-zeng JU Yin SHI Ji-bin JIANG Qi LI Li-ping YUAN Jing WU Tang-chun CHEN Xue-min |
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| Institution: | CHEN Lan~(1,2) XU Guo-jian~3 ZHANG Yu-zeng~(1,2) JU Yin~(1,2) SHI Ji-bin~(1,2) JIANG Qi~(1,2) LI Li-ping~(3*) YUAN Jing~(1,2*) WU Tang-chun~(1,2) CHEN Xue-min~(1,2) (1.Department of Occupational , Environmental Health,School of Public Health,Tongji Medical College,Huazhong University of Science , Technology,Hubei,Wuhan 430030,China,2. The MOE Key Lab of Environment , Health,Chin... |
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| Abstract: | Objective]To investigate the leyels of lead,cadmium and copper in blood and urine samples among residents in an electronic waste recycling site as well as frequencies of micronucleated binucleated cells in those subjects.Methods]We recruited a total of 138 subjects,of which 58 subjects(44 for male,14 for female)with average age of 33.0 years,from the e-waste recycling site(exposed group)and 80 farmers(41for male,39 for female)with average age of 43.7 years,from a village that located 50km away from the re... |
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| Keywords: | e-waste blood lead blood cadmium serum copper urine lead urine cadmium urine copper MNed BNC |
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