Klebsiella pneumoniae carriage in low-income countries: antimicrobial resistance,genomic diversity and risk factors |
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| Authors: | Bich-Tram Huynh Virginie Passet Andriniaina Rakotondrasoa Thierno Diallo Alexandra Kerleguer Melanie Hennart |
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| Affiliation: | 1. UMR 1181 “Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases”(B2PhEID). Institut Pasteur, INSERM, University of Versailles Saint-Quentin , France;2. Institut Pasteur , Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France;3. Experimental Bacteriology Unit, Institut Pasteur Madagascar;4. Laboratory of Medical Biology, Institut Pasteur de Dakar , Dakar, Senegal;5. Medical Biology Unit, Institut Pasteur du Cambodge , Phnom Penh, Cambodia |
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| Abstract: | ABSTRACT Background Klebsiella pneumoniae (hereafter, Kp) is a major public health threat responsible for high levels of multidrug resistant (MDR) human infections. Besides, Kp also causes severe infections in the community, especially in Asia and Africa. Although most Kp infections are caused by endogenous intestinal carriage, little is known about the prevalence and microbiological characteristics of Kp in asymptomatic human carriage, and attached risk factors including environmental sources exposure. |
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| Keywords: | Klebsiella pneumoniae carriage antibiotic resistance genomic diversity community low-income countries |
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