Novel adjuvant action of lipopolysaccharides that possess mannose homopolysaccharides as O-specific polysaccharides on immune responses to nonimmunogenic autoantigens in mice. |
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| Authors: | T Yokochi M Fukada M Kawai Y H Zhang G Z Jiang K Takahashi |
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| Affiliation: | Department of Microbiology, Aichi Medical University School of Medicine, Japan. |
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| Abstract: | The adjuvant action of various lipopolysaccharides on immune responses to syngeneic tissue extract in mice was examined. Only lipopolysaccharides possessing the linear mannose homopolysaccharides as O-specific polysaccharides exhibited definite adjuvant action on immune responses to the autoantigens. The intensity of this adjuvant activity of lipopolysaccharide from Klebsiella O3 seemed to be the strongest. |
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