门电路心血池显像结合超声心动图评估原发性高血压病人的左室舒张功能

应用９９ｍＴｃ－ＲＢＣ门电路心血池显像（ＧＢＰＩ）结合超声心动图（ＵＣＧ）对１００例单纯原发性高血压（Ⅱ期）病人和４２例正常人进行左室舒张功能测定，发现：（１）高血压组的ＧＢＰＩ的最大充盈率（ＭＦＲ）与正常组比较显著降低（Ｐ＜０．０１）；（２）ＵＣＧ的Ａ／Ｅ比值，两组比较无显著差异，Ａ／Ｅ与ＬＶＭＩ或其他指标均无相关；（３）高血压组的ＭＦＲ低于正常均值（２．４１ＥＤＶ／Ｓ）的占８６％，其中ＬＶＭＩ高于正常值（男１００．２ｇ／ｍ２，女８６ｇ／ｍ２）的占８９．０％（７７／８６）；高血压组Ａ／Ｅ比值高于正常值（０．６９）的占６４％，其中ＬＶＭＩ高于正常值的占６２．５％。用ＧＢＰＩ的指标ＭＦＲ结合ＵＣＧ的指标Ａ／Ｅ比值来检测左室舒张功能，对原发性高血压的左室舒张功能的评估，有较大的实用价值，尤以ＭＦＲ指标更为可靠。

Evaluation or Left Ventricular Function During Diatole in Patients with Primary Hypertension by Radionuclide Gated Blood Pool Imaging and Echocardiography

Left ventricular diastolic function of 100 cases of primary hypertension(PHG)and 42 normal pcrsons(NPG)were examined by radionuclide gated blood pool imaging(GBPI)and echocardiography(UCG).The results showed that the maximal filling rate(MFR)in PHG was significantly lower than that in NPG(P<0.01),and MFP of PHG was negative correlation with left ventricular mass index (LVMI)of UCG(r=-0.260,t=2.6655,P<0.05).The mean value of A/E between PHG and NPG Showed no difference(P>0.05)and no correlation with mean value of LVMI of other indexes.The MFR of 86% cases of PHG was lower than mean value of NPG and the LVMI of 89%cases of PHG was higher than normal value.The A/E of 64%of PHG was higher than normal value and the LVMI of 63%higher than normal only;It is suggested that MFR of the GBPI is a good index for assessment of left ventricular filling of primary hypertension.