| 头孢克肟致药品不良反应分析 |
| |
| 引用本文： | 龙敏,张丹,陈蓉.头孢克肟致药品不良反应分析[J].中国药房,2012(6):561-562. |
| |
| 作者姓名： | 龙敏 张丹 陈蓉 |
| |
| 作者单位： | [1]成都市第六人民医院,成都610051 [2]成都市妇女儿童中心医院,成都610000 [3]成都市木综厂职工医院,成都610081 |
| |
| 摘 要： | 目的:探讨头孢克肟致药品不良反应(ADR)发生的特点及规律。方法:收集国内医药期刊有关头孢克肟致ADR个案报道10例并汇总3家医院2000-2010年上报的头孢克肟致ADR报告79例,共89例,进行分析、评价。结果:ADR临床表现方面,以皮肤及其附件损害居首位(占41.57%),其次为神经系统损害(占19.10%)及消化系统损害(占15.73%);以≤10岁儿童(48.31%)和序贯用药(46.07%)报道率最高;约38.20%的ADR发生在用药48h后。结论:临床应重视头孢克肟引起的ADR,用药时应加强对患者的观察,以减少严重ADR的发生。
|
| 关 键 词： | 头孢克肟 药品不良反应 分析 |
Analysis of Adverse Drug Reactions Induced by Cefixime |
| |
| LONG MinThe Sixth People＇s Hospital of Chengdu,Chengdu,China ZHANG DanThe Women and Children＇s Central Hospital of Chengdu,Chengdu,China CHEN Rong.Analysis of Adverse Drug Reactions Induced by Cefixime[J].China Pharmacy,2012(6):561-562. |
| |
| Authors: | LONG MinThe Sixth People＇s Hospital of Chengdu Chengdu China ZHANG DanThe Women and Children＇s Central Hospital of Chengdu Chengdu China CHEN Rong |
| |
| Institution: | LONG Min(The Sixth People＇s Hospital of Chengdu, Chengdu 610051, China) ZHANG Dan(The Women and Children＇s Central Hospital of Chengdu, Chengdu 610000, China) CHEN Rong(Staff-worker Hospital of Muzong Factory in Chengdu, Chengdu 610081, China) |
| |
| Abstract: | OBJECTIVE： To investigate the characteristics and regularity of ADR induced by cefixime. METHODS： 10 cefixime-induced ADR case reports were collected from domestic medical journals. 79 cefixime-induced ADR cases reported by 3 hospitals during 2000--2010 were summarized. A total of 89 ADR cases were analyzed and evaluated. RESULTS： Of total 89 cases of ADR, lesion of skin and appendants took up the biggest proportion （accounting for 41.57% ）, followed by nervous system injury （accounting for 19.10% ） and digestive system injury （accounting for 15.73% ）. 48.31% were occurred in children below 10 years old; 46.07% were in sequential therapy. About 38.20% occurred after 48 hours. CONCLUSION： It is necessary to pay attention to ADR induced by cefixime and strengthen observation during medication in order to reduce the serious ADR. |
| |
| Keywords: | Cefixime Adverse drug reactions Analysis |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
