河北省流行性乙型脑炎流行病学及病原特征研究

目的分析河北省流行性乙型脑炎（乙脑）的流行特征,探讨病原型别,为有效控制乙脑提供科学依据。方法对乙脑监测管理系统信息、个案调查资料及实验室检测数据进行综合分析,对阳性脑脊液标本采用RT-PCR方法进行分型。结果2006年发病率、病死率较2005年有较大幅度上升;发病季节性特征明显,发病多为15岁以下的儿童,RT-PCR分型结果显示病例脑脊液标本感染乙脑病毒为Ⅲ型病毒,与我国常见型别一致。结论2006年河北省乙脑疫情加重,但流行特征仍符合乙脑的一般流行规律。感染的乙型脑炎病毒为Ⅲ型病毒。加强对15岁以下高危人群的疫苗接种,是防控乙脑的关键环节。

Analysing the epidemic and etiology characteristics of Japanese Encephalitis in Hebei Province in 2006

Objective By analysing the epidemic characteristics and etiological type of Japanese Encephalitis （JE） in 2006 in Hebei province to provide scientific evidence for its prevention and control.Methods Using epidemic situation surveillance administ ration system and JE cases questionnaire and laboratory assay information to analyze the result of JE epidemic trend. The CSF positive samples were genotyped by RT-PCR.Results The morbidity rate,fatality in Hebei Province in 2006 year, were more higher than that in 2005 year. The season peak of cases were obviously. In all cases, 0-14 years old children cases account for 54.05%. The result of RT-PCR for CSF samples were JE virus m type, and to accord with the popular strains in China. Conclusion The JE morbility and death in 2006 year were severity compared with up year, but the epidemic characteristics were correspond the JE general rule. JE virus in Hebei Province were Ⅲ type. Strengthen implementing to the 0 - 14 years old children to JE vaccine and reduce the morbidity were the key measure.