46,XY性发育疾病的研究进展

46,XY性发育疾病是临床上一类复杂问题,不仅涉及医疗,也关系着社会、伦理等诸多方面,是一个需要长期甚至终生进行身心随访和诊治的疾病。如能早期诊断、合理治疗,不但可使患者第二性征适当发育,而且可有效防止性腺恶变的可能。近年来由于环境污染等因素的影响,46,XY性发育疾病的发生率在全球范围呈上升趋势,临床应加深对其的认识并提高警惕,及早诊治,最大程度地改善患者预后。本文结合其病因、新分类及诊疗方面的研究现状作一综述。

Progress in researches on 46,XY disorders of sexual development

46,XY disorders of sexual development (46,XY DSD) are a group of complicated clinical conditions,which involve medical care,society,ethics and many other aspects.As chronic diseases,they necessitate long-term or even lifelong physical and mental follow-up and treatment.Early diagnosis and reasonable treatment could not only achieve appropriate development of the secondary sexual characteristics,but also effectively prevent gonadal malignancy.In recent years,environment pollution and other factors are contri...