| 尿白细胞介素6水平与2型糖尿病合并尿路感染相关 |
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| 引用本文： | 邓云,冯晓波,彭蓉,俞伟红,邹立军,杨丽娟,成伟,何蕊骋. 尿白细胞介素6水平与2型糖尿病合并尿路感染相关[J]. 中华内分泌代谢杂志, 2011, 27(3). DOI: 10.3760/cma.j.issn.1000-6699.2011.03.006 |
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| 作者姓名： | 邓云 冯晓波 彭蓉 俞伟红 邹立军 杨丽娟 成伟 何蕊骋 |
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| 作者单位： | 上海市第七人民医院内分泌科,200137 |
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| 摘 要： | 研究尿细胞因子水平与糖尿病患者尿路感染发生的相关性.对156例2型糖尿病女性患者测定尿白细胞介素6(IL-6)水平并随访6个月,分析不同基线水平组尿路感染发病率的差异.尿IL-6浓度四分位最高组尿路感染发生率显著低于最低组(13.5%对37.8%,P＜0.05).尿IL-6水平异常是糖尿病患者易并发尿路感染的可能机制之一.Abstract：The association of urinary cytokine concentration with the incidence of urinary tract infection in patients with diabetes mellitus was explored. Urinary interleakin-6 (IL-6) level in 156 female type 2 diabetes mellitus patients was tested and followed up for 6 months. The incidence of urinary tract infection between the top quartile of baseline urinary cytokine concentration with the bottom quartile was compared. The incidence of top quartile of urinary IL-6 concentration at baseline was significantly lower than that of bottom quartile ( 13.5% vs 37.8%, P＜0.05 ). Abnormality of urinary IL-6 concentration may be involved in the mechanism leading to higher prevalence of urinary tract infection in patients with diabetes mellitus.
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| 关 键 词： | 糖尿病 尿路感染 白细胞介素6 |
Urinary interleukin-6 level was associated with urinary tract infection in patients with type 2 diabetes mellitus |
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| DENG Yun,FEN Xiao-bo,PENG Rong,YU Wei-hong,ZOU Li-jun,YANG Li-juan,CHENG Wei,HE Rui-pin. Urinary interleukin-6 level was associated with urinary tract infection in patients with type 2 diabetes mellitus[J]. Chinese Journal of Endocrinology and Metabolism, 2011, 27(3). DOI: 10.3760/cma.j.issn.1000-6699.2011.03.006 |
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| Authors: | DENG Yun FEN Xiao-bo PENG Rong YU Wei-hong ZOU Li-jun YANG Li-juan CHENG Wei HE Rui-pin |
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| Abstract: | The association of urinary cytokine concentration with the incidence of urinary tract infection in patients with diabetes mellitus was explored. Urinary interleakin-6 (IL-6) level in 156 female type 2 diabetes mellitus patients was tested and followed up for 6 months. The incidence of urinary tract infection between the top quartile of baseline urinary cytokine concentration with the bottom quartile was compared. The incidence of top quartile of urinary IL-6 concentration at baseline was significantly lower than that of bottom quartile ( 13.5% vs 37.8%, P＜0.05 ). Abnormality of urinary IL-6 concentration may be involved in the mechanism leading to higher prevalence of urinary tract infection in patients with diabetes mellitus. |
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| Keywords: | Diabetes mellitus Urinary tract infection Interleukin-6 |
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