大鼠隔－斜带复合体中含小白蛋白蛋白和含胆碱乙酰化酶的神经元

用免疫细胞化学ＰＡＰ法，对成年大白鼠隔－斜带（Ｓ－ＤＢ）复合体中，含小白蛋白（ＰＶ）神经元的分布和形态学进行了研究，并与含胆碱乙酚化酶（ＣｈＡＴ）神经元的观察进行了比较。含ＰＶ神经元主要位于内侧隔核（ＭＳ）、斜带垂直支（ｖＤＢ）和斜带水平支（ｈＤＢ）。ＰＶ免疫反应神经元的形状和大小在Ｓ－ＤＢ复合体的各个核区或同一核区都不相同，表明这些神经元具有多样的形态学特征。在整个Ｓ－ＤＢ复合体中，含ＰＶ和含ＣｈＡＴ神经元的比例，各占ＰＶ和ＣｈＡＴ阳性反应细胞总数的４７／和５３／，在ＭＳ、ｖＤＢ和ｈＤＢ中，ＰＶ免疫反应神经元的比例分别为３８％、５４％和５９．５％，其余为含ＣｈＡＴ的胆碱能神经元。

NEURONS CONTAINING PARVALBUMINAND CHOLINE ACETYLTRANSFERASE IN THESEPTAL-DIAGONAL BAND COMPLEX OF THE RAT

he morphology and distrution of Parvalbumin (PV)-containing neurons of the septal-diagonal band complex of the adult rat brain have been studied by immunocytochemical PAPmethod ,and the findings were comared with observation on choline acetyltransferase(ChAT_-immunoreactive neurons PV-immunoreactive neurons were mainly located in the medial septal nucleus (MS),the nucleus of the vertical limb of the diagonal band (vDB) and the nucleus of the horizontal limb of the diagonal band (hDB),The PV-immunoreactive neu-rons displayed very different sizes and forms among the various seatal nuclei and within each of them ind cating that they do not belong to a single mophological class of neurons theproportions of PV-and ChAT-containing neurons were about 47% and 53% the total positive neurons in the whole septal-diagonal band complex. Abaut 38,54% and 59. 5% of theParvalbumin-imunoreactive neurons were present in the MS, vDB and hDB, respectively,while the remaining neurons in these regions were all ChAT immunoreactive Available stud-ies have been shown that most PV-containing neurons are GAEAergic. The present study ofthe morphology and distribution of PV-or PV-containing GABAeigic and ChAT-containingcholinergic neurons in the septal-diagonal band complex will serve as a useful guide for fu-ture morphological and electrophysiogical studies.