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产杀白细胞素金黄色葡萄球菌感染的研究现状
引用本文:张文先,吴本权. 产杀白细胞素金黄色葡萄球菌感染的研究现状[J]. 国外医学:内科学分册, 2007, 34(8): 448-451
作者姓名:张文先  吴本权
作者单位:中山大学附属第三医院呼吸内科,广东广州510630
摘    要:国外多数回顾性研究发现产杀白细胞素(PVL)金黄色葡萄球菌感染有着特有的临床表现,特别是产PVL金黄色葡萄球菌相关性坏死性肺炎可能为一新现的临床疾病,由此PVL在金黄色葡萄球菌感染中的致病研究日益受到重视.本文就目前对产PVL金黄色葡萄球菌感染的致病机制、流行病学、检测和防治等问题研究作一综述.

关 键 词:葡萄球菌,金黄色  葡萄球菌感染  杀白细胞素  杀白细胞素类
文章编号:1004-2369(2007)08-0448-04
修稿时间:2007-01-18

The present status of study of Panton-Valentine leukocidin-producing Staphylococcus aureus infections
ZHANG Wen-xian,WU Ben-quan. The present status of study of Panton-Valentine leukocidin-producing Staphylococcus aureus infections[J]. Foreign Medical Sciences(Section of Internal Medicine), 2007, 34(8): 448-451
Authors:ZHANG Wen-xian  WU Ben-quan
Affiliation:Department of Respiratory Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China
Abstract:Some retrospective studies have proved that the clinical situations of Panton-Valentine leukocidin(PVL)-producing Staphylococcus aureus infections are distinctive,especially necrotizing pneumonia caused by PVL-positive S aureus seems to be a specific disease entity with a poor prognosis.PVL has been associated with epidemic CA-MRSA stains causing skin and soft tissue infections,necrotizing pneumonia and lethal necrotizing fasciitis.This article reviews the reseaches on the PVL-producing Staphylococcus aureus infections of the pathogenic mechanism,epidemiology,detection,prevention and theraphy,etc.
Keywords:Staphylococcus aureus  Staphylococcus infections  PVL(Panton-Valentine Leukocidin)  Leukocidins
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