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| 人参二醇组皂甙及游泳训练对大鼠股四头肌α-肌动蛋白mRNA表达的影响 | |
| 引用本文： | 杨柯 赵丹 李峰 王志农 赵雪俭 陈燕萍 马兴元. 人参二醇组皂甙及游泳训练对大鼠股四头肌α-肌动蛋白mRNA表达的影响[J]. 中国病理生理杂志, 2002, 18(8): 942-945 |
| 作者姓名： | 杨柯 赵丹 李峰 王志农 赵雪俭 陈燕萍 马兴元 |
| 作者单位： | 1. 吉林大学基础医学院生殖病生研究室,吉林长春 130021; 2. 吉林大学基础医学院天然药物化学研究室,吉林长春 130021 |
| 基金项目： | 卫生部科研基金资助项目(No. 98-2-182) |
| 摘 要： | 目的:观察大鼠7周大负荷游泳训练及人参二醇组皂甙(PDS)对大鼠股四头肌α-肌动蛋白mRNA表达的影响。方法:采用Northernblot分析7周大负荷游泳训练后恢复期大鼠股四头肌α-肌动蛋白mRNA表达水平及PDS对其影响。结果:α-肌动蛋白mRNA杂交信号的扫描积分光密度值(A),运动·盐水组较安静组略强;运动·PDS,扫描积分光密度值(A)显著强于运动·盐水组和安静组,运动·甲睾组与运动·盐水组表达无明显差异。结论:PDS可提高长期耐力运动大鼠股四头肌α-肌动蛋白mRNA表达,从而提高耐力运动能力;长期应用外源性雄激素对耐力训练大鼠股四头肌α-肌动蛋白无明显提高,这可能与外源睾酮对内源性睾酮分泌的抑制有关。 |
| 关 键 词： | 耐力运动 肌 肌蛋白质类 人参 |
| 文章编号： | 1000-4718(2002)08-0942-04 |
| 收稿时间： | 2001-03-22 |
| 修稿时间： | 2001-03-22 |
Effects of prolonged heavy load swimming and the Panaxadiol saponins on expression of α-actin of quadriceps in rats |
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| YANG Ke,ZHAO Dan,LI Feng,WANG Zhi-nong,ZHAO Xue-jian,CHEN Yan-ping,MA Xing-yuan. Effects of prolonged heavy load swimming and the Panaxadiol saponins on expression of α-actin of quadriceps in rats[J]. Chinese Journal of Pathophysiology, 2002, 18(8): 942-945 | |
| Authors: | YANG Ke ZHAO Dan LI Feng WANG Zhi-nong ZHAO Xue-jian CHEN Yan-ping MA Xing-yuan |
| Affiliation: | 1. Department of Pathophysiology, School of Medical Science of Jilin University Changchun 130021, China; 2. Department of Natural Medicine, School of Medical Science of Jilin University Changchun 130021, China |
| Abstract: | AIM: To study the effects of 7 weeks prolonged haevy load swimming and Panaxadiol Saponins (PDS) on the expression of α-actin in quadriceps muscle of thigh in rats. METHODS: After 7 weeks prolonged heavy load swimming training, the expression of α-actin in quadriceps muscle of thigh was quantitatively examined by Northern blotting analysis in the condition with or without PDS treatment. RESULTS: The expression of α-actin in rat quadriceps muscle of thigh in exercise+PDS group was significantly higher than that in sedentray control group and exercise+saline group at 24th hour after intensive training. No statistical difference between exercise+androsan group and exercise+saline group was observed.CONCLUSION: PDS enhanced α-actin expression in quadriceps muscle of thigh in rats. |
| Keywords: | Endurance exercise Muscles Muscle proteins Ginseng |
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