| 射干抗病毒口服液的质量控制研究 |
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| 引用本文： | 贾佳,陈翠,苏华,任海祥,王曙东.射干抗病毒口服液的质量控制研究[J].中国药业,2013,22(10):67-68. |
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| 作者姓名： | 贾佳 陈翠 苏华 任海祥 王曙东 |
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| 作者单位： | 中国人民解放军南京军区南京总医院制剂科,江苏南京,210002 |
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| 摘 要： | 目的研究射干抗病毒口服液的质量控制方法。方法采用薄层色谱法对方中射干、茵陈进行定性鉴别,采用高效液相色谱法对制剂中的绿原酸进行含量测定。结果薄层色谱鉴别的色谱斑点清晰、阴性对照无干扰;绿原酸质量浓度在20.30～121.80μg/mL范围内与峰面积具有良好线性关系,r=0.999 9,平均回收率为100.41%,RSD为1.20%(n=6)。结论该法简便、准确、重复性好,可有效控制制剂的质量。
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| 关 键 词： | 射干抗病毒口服液 薄层色谱鉴别 绿原酸 高效液相色谱法 |
Study on Quality Control of Shegan Antiviral Oral Solution |
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| Jia Jia
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Chen Cui
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Su Hua
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Ren Haixiang
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Wang Shudong.Study on Quality Control of Shegan Antiviral Oral Solution[J].China Pharmaceuticals,2013,22(10):67-68. |
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| Authors: | Jia Jia Chen Cui Su Hua Ren Haixiang Wang Shudong |
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| Institution: | (Department, of Hospital Preparations, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu, China 210002) |
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| Abstract: | Objective To perform the study on the quality control of Shegan Antiviral Oral Solution. Methods Blackberrylily rhizome and herba artemisiae scopariae in Shegan Antivirai Oral Solution were qualitatively identified by TLC. The content of caffeotannic acid was determined by HPLC. Results The developed TLC spots were clear and free from interference of negative sample. The linear range of caffeotannic acid was 20. 30-121.80 μg/mL, r=0. 999 9. The average recovery rate was 100.41%, RSD was 1.20%. Conclusion This method is simple,accurate and better reproducible,which can be used for the quality control of Shegan Antiviral Oral Solution. |
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| Keywords: | Shegan Antiviral Oral Solution TLC caffeotannic acid HPLC |
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