固尔苏治疗新生儿呼吸窘迫综合征30例临床观察

目的观察固尔苏治疗新生儿呼吸窘迫综合征的临床疗效。方法将60例新生儿呼吸窘迫综合征患者随机分为2组。对照组30例予常规西医治疗,治疗组30例在对照组治疗基础上加用固尔苏治疗。观察2组用药后辅助呼吸时间及机械通气时间,比较2组氧分压[P（O2）]、二氧化碳分压[P（CO2）]、pH值、动脉血氧饱和度（SaO2）及临床疗效。结果治疗组治疗后P（O2）、pH值及SaO2均高于对照组治疗后（P〈0．05）。治疗组治疗后辅助呼吸时间、机械通气时间均短于对照组治疗后（P〈0．05）。治疗组总有效率86．7％,对照组总有效率66．7％,2组总有效率比较差异有统计学意义（P〈0．05）,治疗组临床疗效优于对照组。结论固尔苏治疗新生儿呼吸窘迫综合征效果显著。

Clinical observation of Curosurf on the treatment of neonatal respiratory distress syndrome

Objective To observe the effect of Curosurf on the treatment of neonatal respiratory distress syn- drome （NRDS）. Methods 60 patients with NRDS were randomly divided into observation group and the control group （30 patients in each）. The control group was given with conventional treatment, but the observation group re- ceived Curosurf on the basis of control treatment. Assisted respiration and duration of mechanical ventilation were ob- served after treatment. Blood gas analysis parameters and clinical efficacy after treatment were compared. Results Assisted breathing and mechanical ventilation time of the observation group were shorter than those in the control group （ P 〈 0.05）. p （ 02 ）, pH value and SaO2 and total effective rate in observation group were higher than those in the control group, the difference was statistically significant（ P 〈 0.05 ）. Conclusion Curosurf has significant effect on the treatment of NRDS.