| 去甲肾上腺素对原位肝移植患者胃黏膜pH值的影响 |
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| 引用本文： | 陈绪贵,曹蕾,王勇.去甲肾上腺素对原位肝移植患者胃黏膜pH值的影响[J].临床麻醉学杂志,2011,27(8). |
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| 作者姓名： | 陈绪贵 曹蕾 王勇 |
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| 作者单位： | 100700,北京军区总医院附属八一脑科医院麻醉科 |
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| 摘 要： | 目的探讨去甲肾上腺素对原位肝移植患者胃黏膜pH值(pHi)的影响。方法原位肝移植手术患者24例,随机均分为去甲肾上腺素组(N组)和多巴胺组(D组),分别于术前(T0)、无肝前期30 min(T1)、无肝期30 min(T2)、新肝期5 min(T3)、90 min(T4)、术毕(T5)记录患者HR、MAP、PaCO2和胃黏膜二氧化碳分压(PgCO2)并计算pHi。结果 T2、T3时D组HR明显增快,MAP显著降低(P<0.05),N组变化差异无统计学意义。T1~T3时两组pHi均明显降低,且D组显著低于N组(P<0.05)。结论原位肝移植术中积极补充容量的同时应用去甲肾上腺素能更有效维护血流动力学稳定,改善胃肠黏膜灌注。
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| 关 键 词： | 去甲肾上腺素 原位肝移植 胃黏膜pH |
Effect of norepinephrine on the gastric intraumucosal pH during orthotopic liver transplantation |
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| CHEN Xu-gui,CAO Lei,WANG Yong.Effect of norepinephrine on the gastric intraumucosal pH during orthotopic liver transplantation[J].The Journal of Clinical Anesthesiology,2011,27(8). |
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| Authors: | CHEN Xu-gui CAO Lei WANG Yong |
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| Institution: | CHEN Xu-gui,CAO Lei,WANG Yong.Department of Anesthesiology,BaYi Brain Affiliated Hospital,Beijing Military Command General Hospital,Beijing100700,China |
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| Abstract: | Objective To investigate the effect of norepinephrine on the gastric intraumucosal pH during orthotopic liver transplantation.Methods Twenty-four adult patients undergoing orthotopic liver transplantation were randomly divided in two groups: dopamine group(group D,n= 12) and norepinephrine group(group N,n=12).Norepinephrine(group N) or Dopamine(group D) was infused respectively to maintain mean arterial blood pressure(MAP) at 60-100 mm Hg during orthotopic liver transplantation.Gastric intramucosal PCO2(PgC... |
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| Keywords: | Norepinephrine Orthotopic liver transplantation Gastric intraumucosal pH |
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