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不同剂量依托咪酯用于老年患者麻醉诱导气管插管时对镇静深度的影响
引用本文:张忱,岳云,吴奇伟,柳娟.不同剂量依托咪酯用于老年患者麻醉诱导气管插管时对镇静深度的影响[J].临床麻醉学杂志,2011,27(8).
作者姓名:张忱  岳云  吴奇伟  柳娟
作者单位:100020,首都医科大学附属北京朝阳医院麻醉科
摘    要:目的观察不同诱导剂量依托咪酯复合舒芬太尼用于老年患者麻醉诱导对镇静深度的影响。方法 65岁以上老年患者60例,按照依托咪酯诱导剂量随机分为四组:A组0.2 mg/kg,B组0.3 mg/kg,C组0.4 mg/kg,D组0.5 mg/kg。观察并记录诱导前(T0)、插管前(T1)、插管即刻(T2)、插管后1 min(T3)、3 min(T4)和5 min(T5)的MAP、HR和BIS变化。结果 A、D组血流动力学波动比B、C组明显。T2~T5时D组BIS明显低于其它三组(P<0.05或P<0.01),T4、T5时A组BIS明显高于其它三组(P<0.01)。结论依托咪酯0.3~0.4 mg/kg复合舒芬太尼0.3μg/kg较适合老年患者麻醉诱导,镇静深度适中,循环较平稳。

关 键 词:镇静深度  麻醉诱导  依托咪酯  脑电双频指数  老年  

Effect of different etomidate doses on hemodynamics and the depth of sedation during anesthesia induction in aged people
ZHANG Chen,YUE Yun,WU Qi-wei,et al..Effect of different etomidate doses on hemodynamics and the depth of sedation during anesthesia induction in aged people[J].The Journal of Clinical Anesthesiology,2011,27(8).
Authors:ZHANG Chen  YUE Yun  WU Qi-wei  
Institution:ZHANG Chen,YUE Yun,WU Qi-wei,et al.Department ofAnesthesiology,Beijing Chaoyang Hospital,Capital Medical University,Beijing100020,China
Abstract:Objective To observe hemodynamic parameters and Bispectral index(BIS) of aged people anesthetized by different doses of etomidate during anesthesia induction and tracheal intubation and to investigate the suitable dose of etomidate for aged people with fewer hemodynamic variations during anesthesia induction and tracheal intubation.Methods Sixty aged patients(> 65 years) were involved and randomly assigned to 4 groups according to the dose of etomidate they received: group A(0.2 mg/kg),group B(0.3 mg/kg),gr...
Keywords:Anaesthesia depth  Anaesthesia induction  Etomidate  Bispectral index  Aged  
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