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钛表面激光快速成形CaTiO3涂层成骨细胞相容性的研究
引用本文:闫娟娟,胡江,吕小卫,周健,高勃.钛表面激光快速成形CaTiO3涂层成骨细胞相容性的研究[J].临床口腔医学杂志,2011,27(12):715-718.
作者姓名:闫娟娟  胡江  吕小卫  周健  高勃
作者单位:1. 第四军医大学口腔医院修复科 陕西西安710032
2. 西北工业大学凝固技术国家重点实验室 陕西 西安710072
基金项目:国家“863”计划项目(2006AA03Z449)
摘    要:目的:探讨激光快速成形技术制备的纯钛表面CaTiO3涂层的成骨细胞相容性。方法:分别制备纯钛表面激光快速成形CaTiO3涂层试件和经表面处理的纯钛试件各6个,采用成骨细胞与材料共培养技术,利用MTT法分别检测成骨细胞在两种材料表面的黏附和增殖数量,并进行统计学分析;利用扫描电镜观察法分别观察成骨细胞在两种材料表面的铺展状态。结果:纯钛表面激光快速成形CaTiO3涂层材料表面成骨细胞的黏附和增殖数量明显高于经表面处理的纯钛(P〈0.05);成骨细胞在经表面处理纯钛表面呈板状平铺,而在CaTiO3涂层表面呈多极性、立体伸展,并表现出更加旺盛的功能状态。结论:激光快速成形技术在纯钛表面制备的CaTiO3涂层能够促进成骨细胞在材料表面的黏附、铺展和增殖。

关 键 词:纯钛  激光快速成形  钛酸钙  涂层  成骨细胞相容性

Study on osteoblast compatibility of CaTiO3 coating fabricated by laser rapid forming
YAN Juan-juan,HU Jiang,LV Xiao-wei,ZHOU Jian,GAO Bo.Study on osteoblast compatibility of CaTiO3 coating fabricated by laser rapid forming[J].Journal of Clinical Stomatology,2011,27(12):715-718.
Authors:YAN Juan-juan  HU Jiang  LV Xiao-wei  ZHOU Jian  GAO Bo
Institution:YAN Juan-juan1,HU Jiang1,LV Xiao-wei2,ZHOU Jian1,GAO Bo1.1.Department of Prosthodontics,College of Stomatology,Fourth Military Medical University,Shaanxi Xi'an 710032,China,2.State Key Laboratory of Solidification Processing,Northwestern Polytechnical University,Shaanxi Xi'an 710072,China.
Abstract:Objective:To study the osteoblast compatibility of CaTiO3 coating fabricated by Laser Rapid Forming on pure titanium.Method:Six pieces of pure titanium coated by CaTiO3 and six species of surfacially treated titanium.Using the technology of culturing osteoblast with artificial material together,the amounts of osteoblast adherence and proliferation on the surface of the two experimental materials were estimated by MTT method,the results were analyzed by statistics method,and the states of osteoblast spreadin...
Keywords:pure titanium  laser rapid forming  calcium-titanate  coating  osteoblast compatibility  
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