Malignant fibrous histiocytoma in the skull--case report. |
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Authors: | S Hatashita A Tajima H Ueno |
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Affiliation: | Juntendo University Urayasu Hospital, Chiba. |
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Abstract: | A 45-year-old male presented with a large calvarial mass caused by a malignant fibrous histiocytoma arising primarily from the frontal bone and extending into the intracranial space. Magnetic resonance imaging revealed a well-demarcated, mottled enhanced bulky tumor with several low-signal separations. He underwent extensive tumor and bone removal, followed by radiation therapy. Histological examination showed pleomorphic spindle cells in a storiform pattern. The tissue stained positive for alpha-1-antitrypsin and alpha-1-antichymotrypsin by immunohistochemical techniques. |
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