Granulocyte colony stimulating factor-producing lung cancer with severe anemia of inflammation |
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Authors: | Koutaro Murakami Yujin Kudo Masatoshi Kakihana Jun Matsubayashi Tetsuya Okano Yoshihisa Shimada Toshitaka Nagao Naohiro Kajiwara Tatsuo Ohira Norihiko Ikeda |
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Affiliation: | 1.Department of Surgery,Tokyo Medical University,Tokyo,Japan;2.Department of Anatomic Pathology,Tokyo Medical University,Tokyo,Japan |
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Abstract: | Granulocyte colony stimulating factor (G-CSF)-producing lung cancer occasionally induces severe inflammation with an abnormally high white blood cell count. Herein, we report a 49-year-old man who suffered from resectable G-CSF-producing non-small cell lung cancer with continuous fever and severe anemia. Red blood cell transfusion was necessary for the anemia of inflammation. The patient underwent complete surgical tumor resection. The histopathological diagnosis was a pleomorphic carcinoma at pathological stage IIB. This is apparently the first successful case of surgical resection of G-CSF-producing lung cancer in a patient with severe anemia and uncontrollable fever. |
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