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心理干预对白癜风患者心理状况及5-羟色胺和去甲肾上腺素水平影响的研究
引用本文:杨娴,李其林,曾凡钦. 心理干预对白癜风患者心理状况及5-羟色胺和去甲肾上腺素水平影响的研究[J]. 岭南皮肤性病科杂志, 2008, 15(6): 320-323
作者姓名:杨娴  李其林  曾凡钦
作者单位:1. 暨南大学附属第四医院/广州市红十字会医院,广东,广州,510220
2. 中山大学附属第二医院,广东,广州,510120
摘    要:目的:对白癜风患者实施心理干预,了解其干预前后的心理状况及5-羟色胺和去甲肾上腺素水平的变化。方法:采用心理健康症状自评量表(SCL-90)、汉密尔顿抑郁量表(HAMD)以及汉密尔顿焦虑量表(HAMA)调查患者干预前后心理状况的变化,及检测患者外周血中5-羟色胺(5-HT)和去甲肾上腺素(NE)水平的变化。结果:SCL-90测评显示白癜风组在躯体化、人际关系、焦虑、抑郁和敌对性项的评分明显高于对照组,差异有统计学意义(P〈0.05);干预后评分较干预前明显下降,差异有统计学意义(P〈0.05)。HAMD、HAMA测评显示:白癜风组得分明显高于对照组,差异有统计学意义(P〈0.05);干预后评分较干预前明显下降,差异有统计学意义(P〈0.05)。白癜风患者接受心理干预后,5-HT和NE水平比治疗前显著上升(均P〈0.05)。结论:白癜风患者可能存在多方面心理障碍,心理干预对其可能有一定的治疗作用。

关 键 词:白癜风  心理干预  5-羟色胺  去甲肾上腺素

The effect of psychological intervention on the psychological state,5-HT and NE in the patients with vitiligo
YANG Xian,LI Qi-lin,ZENG Fan-qin. The effect of psychological intervention on the psychological state,5-HT and NE in the patients with vitiligo[J]. Southern China Journal of Dermato-Venereology, 2008, 15(6): 320-323
Authors:YANG Xian  LI Qi-lin  ZENG Fan-qin
Affiliation:YANG Xian1,LI Qi-lin1,ZENG Fan-qin2(1.The Fourth Hospital Affiliated to Jinan University/Guangzhou Red Cross Hospital,Guangzhou 510220,China,2.The Second Hospital Affiliated to Sun Yat-Sen University,Guangzhou 510120,China)
Abstract:Objective:To investigate the influence of psychological intervention on psychological state,5-HT and NE in the patients with vitiligo. Methods:SCL-90,HAMD and HAMA were used to investigate the psychological state of the vitiligo patients group and the control group before and after psychological intervention.At the same time,the blood levels of 5-HT and NE were also measured.Results:Scores of somatization,interpersonal sensitivity,depression,anxiety and hostility of the patients with vitiligo in SCL-90 were...
Keywords:vitiligo  psychological intervention  5-HT  NE  
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