| 牙菌斑液成分在判断个体龋易感性中的作用 |
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| 引用本文： | 董艳梅,高学军. 牙菌斑液成分在判断个体龋易感性中的作用[J]. 中华口腔医学杂志, 2001, 36(4): 277-280 |
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| 作者姓名： | 董艳梅 高学军 |
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| 作者单位： | 北京大学口腔医学院牙体牙髓科 |
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| 基金项目： | 国家自然科学基金资助项目(39870843) |
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| 摘 要： | 目的研究糖代谢后牙菌斑液化学成分与龋的关系,探求判别个体龋易感性中的因子.方法6～7岁儿童,无龋(dmfs=0)12名,高龋(dmfs≥10)6名,低龋(3≤dmfs＜10)7名.毛细管电泳技术(Beckman,Pace5000)检测有机酸、磷酸和无机阳离子.结果无龋组乳酸和低pKa酸的水平显著低于低龋组(P=0.002)和高龋组(P=0.01).多元逐步回归法和Logist回归法筛选出乳酸为龋的判别因子(P=0.0644).结论糖代谢7min后菌斑液中乳酸浓度的变化具有判断个体对龋易感程度的作用.
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| 关 键 词： | 龋病易感性 电泳 毛细管 牙菌斑 |
| 修稿时间： | 2000-10-18 |
Effect of composition in plaque fluid on evaluation of individual caries risk |
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| DONG Yanmei,GAO Xuejun. Effect of composition in plaque fluid on evaluation of individual caries risk[J]. Chinese journal of stomatology, 2001, 36(4): 277-280 |
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| Authors: | DONG Yanmei GAO Xuejun |
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| Affiliation: | Department of Operative Dentistry and Endodontics, Peking University School of Stomatology, Beijing 100081, China. |
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| Abstract: | Objective To study the association of composition in plaque fluid after sugar challenge wi th caries susceptibility in order to find predictors of identifying individual c aries risk. Methods Children aged 6-7, caries free 12, high ca ries 6 and low caries 7 were studied. Plaque composition were determined by capi llary electrophoresis. Results Contents of lactic acid and lower pKa acids were signif icantly lower in caries free group than in low caries (P=0002) and high ca ries (P=001) groups. It demonstrated by multiple regression and Logistic r egression that lactic acid content could be a predictor of individual caries ris k. Conclusions Content of lactic acid in plaque fluid 7 minut es after sugar challenge could be a preditor of individual caries risk. |
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| Keywords: | Dental caries susceptibility Electrophoresis c apillary Dental plaque |
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