| 透皮吸收促进剂对奥沙普秦渗透性影响的研究 |
| |
| 引用本文： | 郭宏,甘勇,李嘉煜,潘卫三. 透皮吸收促进剂对奥沙普秦渗透性影响的研究[J]. 中国药学杂志, 2001, 36(9): 606-608 |
| |
| 作者姓名： | 郭宏 甘勇 李嘉煜 潘卫三 |
| |
| 作者单位： | 沈阳药科大学药学系, |
| |
| 摘 要： | 目的 研究促进剂对奥沙普秦渗透性的影响。方法 采用Valia-Chien扩散池进行大鼠离体皮肤的体外渗透实验。结果 透皮吸收促进剂和不同浓度的月桂氮艹（上）卓（下）酮对奥沙普秦的渗透性均有促进作用。结论 月桂氮酮对奥沙普秦透皮吸收的促进作用具有浓度依赖性。
|
| 关 键 词： | 奥沙普秦 促进剂 经皮渗透 |
| 文章编号： | 1001-2494(2001)09-0606-03 |
| 收稿时间： | 2001-03-26; |
| 修稿时间： | 2001-03-26 |
Investigation on the effects of penetration enhancers on permeation of oxaprozin in vitro |
| |
| GUO Hong,GAN Yong,LI Jia-yu,PAN Wei-san. Investigation on the effects of penetration enhancers on permeation of oxaprozin in vitro[J]. Chinese Pharmaceutical Journal, 2001, 36(9): 606-608 |
| |
| Authors: | GUO Hong GAN Yong LI Jia-yu PAN Wei-san |
| |
| Affiliation: | Shenyang Pharmacutical University,Shenyang 110015,China |
| |
| Abstract: | OBJECTIVE To study the effects of enhancers on the transdermal delivery of oxaprozin.METHODS The penetration ra te of oxaprozin through rat skin in vitro was measured using Valia-Chien di ffusion cell.RESULTS The enhancers and different concentrati ons of laurocapram(Azone) 1%,3%,5%,10% improved the transdermal delivery of o xaprozin.CONCLUSION The transdermal delivery of oxaprozin wa s improved which related to the concentrations of laurocapram. |
| |
| Keywords: | oxaprozin enhancer penetration |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国药学杂志》浏览原始摘要信息 |
|
点击此处可从《中国药学杂志》下载免费的PDF全文 |
