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18F-FDGPET/CT与多层螺旋CT在进展期胃癌术前TNM分期的对比研究
引用本文:黄源,林进令,陈大勇,刘志明,陈俊强. 18F-FDGPET/CT与多层螺旋CT在进展期胃癌术前TNM分期的对比研究[J]. 国外医学(外科学分册), 2010, 0(3): 161-165,F0003
作者姓名:黄源  林进令  陈大勇  刘志明  陈俊强
作者单位:广西医科大学第一附属医院胃肠外科,南宁530021
基金项目:广西科学基金资助项目(桂科攻0719006-2-10)
摘    要:目的应用18F-FDGPET/CT(PET/CT)与多层螺旋cT对进展期胃癌术前TNM分期进行对比研究,以期更客观地评估术前分期,指导治疗。方法对术前行PET/CT检查的39例及MSCT检查的40例进展期胃癌,分别进行术前TNM分期,将检测结果与术中所见及病理进行对照。结果PET/CT对原发灶、区域淋巴结、N3转移淋巴结的准确率分别为92.3%、66.7%、100.0%;而MSCT诊断的准确率分别为82.0%、50.0%、62.5%。结论(1)PET/CT和多层螺旋CT对原发灶、区域淋巴结转移的准确率都较高,差异无统计学意义,由于多层螺旋cT临床应用广泛且费用远低于PET/CT,是首选的检测手段;(2)PET/CT对N3转移淋巴结、远处转移灶检测的准确率明显高于多层螺旋cT,为临床提供更为全面客观的术前分期,指导治疗;(3)由于PET/CT也存在一定假阴性,结合腹腔镜检可减少或避免不必要的剖腹术。

关 键 词:18F—FDG  PET/CT  多层螺旋CT  进展期胃癌  对比研究

Diagnostic value of 18F-FDG PET/CT in the preoperative advanced gastric carcinoma comparing with multi - slice spird computed tomography
Affiliation:HUAN GYuan , LIN Jin-ling, CHEN Da-yong, LIU Zhi-ming, CHEN Jun - qiang (Department of Gastroenterology Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China)
Abstract:Objective Evaluate the diagnostic value of PET/CT in the preoperative advanced gastric carcinoma comparing with muh;-sliee spiral computed tomography. Methods Thirty -nine advanced gastric carcinoma patients taking PET/CT and abstract 40 advanced gastric carcinoma patients performing MSCT be- fore operation,were done the TNM staging, and the results were compared with the operation histopathology. Results For diagnosing primary lesions, regional lymph nodes, N3 lymph nodes , PET/CT was accurate in 92.3% , 66.7% and 100.0%. Instead, MSCT was accurate in 82.0%, 50.0% and 62.5%. Conclusions ( 1 ) PET/CT and MSCT have high accuracy in diagnosing primary lesions and regional lymph nodes. But for detecting the N3 lymph nodes and distant metastasis, PET/CT has higher accuracy than MSCT. PET/CT combining abdominoscopy may decrease or avoid exploratory laparotomy.
Keywords:18F-FDG PET/CT  MSCT  Advanced gastric carcinoma  Correlation research
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