阿托品的临床新用途

阿托品是抗胆碱药,通过阻断效应器官上的M受体而发挥作用,大剂量时对N1受体也有一定阻断作用,随着剂量的增加,各器官对它的敏感度表现为：腺体,瞳孔,膀胱和胃肠道平滑肌,心脏,中枢.在临床用于抢救中毒性休克,治疗锑中毒引起的阿-斯综合征,解除有机磷中毒症状,治疗内脏平滑肌痉挛而致的绞痛,麻醉前减少腺体分泌,扩瞳验光等.近年来,临床发现了许多新用途.现综述如下.

Atropine clinical new use

The atropine is the anti--choline medicine, through blocks on the effect organ the M aceeptor plays the role, when the large dose also has to the N1 acceptor blocks certainly the function, along with the dosage increase, various organs to its sensitivity performance is： Gland, pupil, urinary bladder and gastro--intestinal tract smooth muscle, heart, main center. In clinical uses in rescuing the toxic shock, Arab League -- Si who the treatment stibium poison causes synthesizes drafts, relieves the organic phosphorus poison symptom, treats the colic which the internal organs smooth myospasm sends, before the anaesthesia reduces the gland secretion, expands the pupil optometry and so on_ In recent years, clinical has discovered many new uses. Presently summarizes as follows.