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64层螺旋CT诊断冠状动脉内斑块
引用本文:王健,祝缮珠,赵琦. 64层螺旋CT诊断冠状动脉内斑块[J]. 中国临床医学, 2008, 15(1): 16-19
作者姓名:王健  祝缮珠  赵琦
作者单位:1. 复旦大学附属中山医院全科医学科,上海,200032
2. 复旦大学公共卫生学院流行病学教研室,上海,200032
摘    要:目的:探讨64层螺旋CT(MSCT)冠状动脉成像对冠状动脉内斑块的诊断能力及冠脉内斑块与与冠状动脉狭窄和冠心病危险因素之间的关系。方法:对2006年接受MSCT冠状动脉成像和选择性冠状动脉造影检查(这两项检查的间隔时间不超过1个月)的113例患者的临床资料进行分析。结果:MSCT检查共发现软斑块74个,钙化斑块128个,混合斑块48个,以冠状动脉近段(67.6%)斑块数量最多,其次为中段(18.4%),伴相应冠状动脉分支血管不同程度狭窄。斑块位置、斑块类型与冠状动脉的狭窄程度无统计学意义。除年龄因素外,冠状动脉内有无斑块组的冠心病危险因素(包括性别、吸烟、高血压、糖尿病、血脂等)无统计学差异。在斑块类型和位置的诊断上,MSCT检查与冠状动脉内超声检查结果完全一致。结论:MSCT可以清晰地显示冠状动脉内斑块的情况,能及早检出不稳定斑块,发现冠状动脉狭窄前的早期冠状动脉病变,对预测和早期诊断冠心病有重要价值,能为临床合理治疗和预防猝死提供及时、重要的信息。

关 键 词:选择性冠状动脉造影术  多层螺旋CT  钙化斑块  软斑块

Diagnosis of Plaque within Coronary Artery by 64-slice Spiral CT Coronary Angiograhy
WANG Jian,ZHU Shanzhu,ZHAO Qi. Diagnosis of Plaque within Coronary Artery by 64-slice Spiral CT Coronary Angiograhy[J]. Chinese Journal Of Clinical Medicine, 2008, 15(1): 16-19
Authors:WANG Jian  ZHU Shanzhu  ZHAO Qi
Abstract:Objective:To explore the capability of 64-slice multi spiral CT coronary artery imaging in inspecting plaque in coronary artery,and the connection between plaques in coronary artery and coronary artery stenosis as well as risk factors of it.Methods:Samples were taken from 113 hospitalized patients who took multi spiral CT coronary artery imaging and selective coronary arteriography tests at intervals of no more than one month.Results:As for the 113 patients,the age and plaque is correlated statistically.For the group with plaque and the group without plaque,there is no statistic correlation between the group and risk factors of coronary heart disease such as gender,smoking and non-smoking,hypertension,diabetes and lipid.Multi spiral CT coronary artery imaging found 74 cases of soft plaques,128 cases of calcific plaques,48 cases of mixed plaques.The largest proportion of the plaques is in the proximal coronary artery,the second largest proportion in the middlepiece,with varied degree of stenosis in branches of related coronary artery.There is no statistic correlation between the type of plaque and the extent of stenosis of coronary artery for different affected areas of coronary artery.10 of the 113 patients received SCA test as well as intravascular ultrasound.The diagnosis of multi spiral CT coronary artery imaging for the type and area of plaque is consistent with the diagnosis of intravascular ultrasound.Conclusion:multi spiral CT coronary artery imaging can clearly show the plaque in the coronary artery and detect unstable plaques at an early stage,thus discover the initial coronary artery affection prior to coronary artery stenosis.This is valuable for prediction and early diagnosis of coronary diseases,and provides useful and timely information for reasonable clinical care and intervention,and prevention of sudden death.
Keywords:Selective coronary arteriography  Multi spiral CT coronary artery imaging  Calcific plaque  Soft plaque
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