定量组织速度显像技术测定二尖瓣环运动与左室整体收缩功能的评价

目的 :应用超声定量组织速度显像 (QTVI)技术测定二尖瓣环运动速度 ,评价其是否与左室整体收缩功能指标左室射血分数 (L VEF)相关。方法 :5 0例冠状动脉疾病患者 (冠心病组 )和 2 5例正常人 (对照组 ) ,从心尖四腔、两腔和长轴切面观中测定后间隔、侧壁、前壁、下壁、前间隔和后壁六个部位的二尖瓣环收缩期平均峰值速度 (Sm)以及心电图 QRS波起始至二尖瓣环收缩波峰值的时间 (Q- Sm) ,并与心尖四腔观单平面改良 Simpson法所测 L VEF作相关性分析。结果 :冠心病组六个部位的二尖瓣环 Sm平均值 (5 .2 1± 1.12 ) cm / sec与 L VEF呈显著正相关 (r=0 .6 6 ,P<0 .0 0 0 1) ,对照组六个部位的 Sm平均值 (6 .0 2± 0 .83) cm/ sec亦与 L VEF显著正相关 (r=0 .6 5 ,P<0 .0 0 0 1)。 Q- Sm和心率则与 L VEF无显著相关性。结论 :应用 QTVI技术测定收缩期二尖瓣环运动可反映左室整体收缩功能 ,有一定临床应用价值

Correlation of Mitral Annular Systolic Motion Velocities with the Global Left Ventricular Systolic Function in Normals and Patients with Coronary Artery Disease

Objective:To evaluate if the mitral annular systolic motion velocities measured by Doppler quantitative tissue velocity image (QTVI)correlated with left ventricular ejection fraction(LVEF).Methods:Twenty five normal subjects and 50 patients with coronary artery disease were studied.The peak systolic mean velocity (Sm)and the time from the electrocardiographic Q wave to the peak systolic mean velocity(Q Sm)were measured at 6 mitral annular sites from 2 dimensional echocardiograms and to compared with LVEF calculated from the modified Simpson formula.Results:There was a significant correlation between the mean Sm and LVEF in the normal subjects( r =0 65, P <0 0001)as well as the patients with coronary artery disease( r =0 66, P <0 0001).Conclusions:Mitral annular systolic motion velocities measured by Doppler QTVI technique should be used to evaluate global left ventricular systolic function.