| 3种药物治疗慢性乙型肝炎的成本-效果分析 |
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| 引用本文： | 李莉,周延安.3种药物治疗慢性乙型肝炎的成本-效果分析[J].药物流行病学杂志,2008,17(5):340-341. |
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| 作者姓名： | 李莉 周延安 |
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| 作者单位： | 武汉大学人民医院药学部,武汉,430060 |
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| 摘 要： | 目的：对拉米夫定、阿德福韦酯、恩替卡韦等3种药物治疗慢性乙型肝炎作成本-效果分析，找出最佳方案。方法：统计11篇临床报告1026例慢性乙型肝炎患者经拉米夫定、阿德福韦酯、恩替卡韦治疗48周的疗效，计算成本，进行成本．效果分析。结果：3种药物的乙肝病毒DNA转阴率分别为42．90％，51．59％，76．09％，成本-效果值分别为121．95、97．04、165．06。结论：阿德福韦酯是治疗慢性乙型肝炎成本-效果较佳。
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| 关 键 词： | 拉米夫定 阿德福韦酯 恩替卡韦 慢性乙型肝炎 |
Cost-effectiveness Analysis of Three Drugs in the Treatment of Chronic Hepatitis B |
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| Li Li,Zhou Yan\''an.Cost-effectiveness Analysis of Three Drugs in the Treatment of Chronic Hepatitis B[J].Chinese Journal of Pharmacoepidemiology,2008,17(5):340-341. |
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| Authors: | Li Li Zhou Yan\'an |
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| Institution: | Li Li,Zhou Yan\'an(Department of Pharmacy,People\'s Hospital of Wuhan University,Wuhan 430060,China) |
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| Abstract: | Objective:To compare the cost-effectiveness ratio among lamivudin(LMV),adefovir dipivoxil(AFD) and entecavir(ETC)in the treatment of chronic hepatitis B to find the best scheme.Method:1026 patients with chronic hepatitis B from 9 reports were given LMV(359 patients),SFD(345 patients)and ETC(322 patients)for 48 weeks.Then a cost-effectiveness analysis was carried out.Result:The cost for LMV was 5 231.52 yuan,the cost for AFD was 5006.4 yuan,and the cost for ETC was 12 559.68 yuan.The therapeutic effects were... |
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| Keywords: | Lamivudine Adefovir dipivoxil Entecavir Chronic hepatitis B Cost-effectiveness analysis |
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