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Outcome following surgery for ophthalmic segment aneurysms
Authors:Bhawani S Sharma  Manish K Kasliwal  Ashish Suri  P Sarat Chandra  Aditya Gupta  VS Mehta
Institution:1. Division of General Academic Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA;2. Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI;3. University of Pittsburgh Graduate School of Public Health, Department of Biostatistics, Pittsburgh, PA;4. Division of Pediatric Radiology, Children''s Hospital of Pittsburgh, Pittsburgh, PA;1. John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ;2. Rutgers New Jersey Medical School, Newark, NJ;3. Capital Health System, Pennington, NJ;1. Department of Neurosurgery, Johns Hopkins University School of Medicine, Zayed Tower, 6115F, 1800 Orleans Street, Baltimore, MD 21287, USA;2. Department of Neurosurgery, Rush University Medical Center, Chicago, IL, USA;1. Hokkaido Neurosurgical Memorial Hospital, Sapporo, Japan;2. Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Abstract:Ophthalmic segment aneurysms account for about 5% of all intracranial aneurysms. Anatomical complexity of the paraclinoid region makes surgical management of aneurysms arising from the ophthalmic segment challenging. This study was carried out to assess the presenting features, complications and outcomes after surgical treatment of ophthalmic segment aneurysms. The authors retrospectively analysed the clinical records of patients with ophthalmic aneurysms treated at our Institute from January 2001 to September 2008, which constituted about 9% (78/850) of all intracranial aneurysms. Of the 78 ophthalmic segment aneurysms, six patients (8%) had giant aneurysms and 19 (24%) patients had multiple aneurysms. Fifty-six patients underwent microsurgery, with direct clipping in most. The mean age was 42 years (range 12–75 years) and the mean follow-up was 8 months (range, 2–93 months). A good outcome was achieved in 46 (83%) patients (Glasgow Outcome Scale GOS] score 4–5) and 17% had a poor outcome (GOS score 1–3) at last follow-up. The overall complication rate was 21% (12/56), most of which were transient complications, with 3.5% (2/56) mortality. Direct microsurgical clipping remains our preferred treatment approach, whenever possible, for ophthalmic segment aneurysms. This surgery has an acceptable complication rate and leads to a good outcome in more than 80% of patients with ophthalmic aneurysms. Use of modern microsurgical instrumentation and endovascular adjuncts can further reduce the surgical morbidity associated with these vascular lesions.
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