术中应用丝裂霉素C治疗翼状胬肉的临床研究

目的：翼状裔肉切除术中局部应用MMC治疗翼状胬肉，以减少翼状胬肉术后复发，采用逆行切除术式降低角膜并发症。方法：局麻下逆行切除胬肉组织，即沿胬肉颈部剪开结膜，去除体部胬肉组织。将浸有0．2mg／ml MMC棉片放于胬肉根部断面，用球结膜覆盖之，3min后反复冲洗后完整切除胬肉头部。结果：行此法治疗病人60例65眼，随访6-22月，未见复发，无角膜并发症。结论：术中应用MMC0．2mg／ml 3min，能有效的抑制结膜纤维组织增生，无角膜并发症和巩膜变薄发生；术式的改进能有效的保护角膜。

Clinical research of using Mitomycin during operation in treating pterygium

Objective To observe the effects of MMC in treating pterygium to reduce the damage to cornea. Methods To cut the cervix of pterygium, wipe off its body, then put one medicine cotton piece which dipped with MMC 0. 2 mg/ml on the wound for 3 minutes, then get off the cotton piece and washed the wound and ablate the head of pterygium. Results The application of the improved operation method and the use of 0. 2 mg/ ml MMC in 60 patients showed that there were no recur- rence and complications after 6 - 22 months. Conclusion The application of 0.2 mg/ mg MMC during operation for 3 minutes could effectively control fiber hyperplasia of conjunctivas and there were no complications on cornea and thinner sclera. The improvement in operation could effec- tively protect the cornea.