Perfusion imaging of the kidney using contrast-enhanced phase-inversion ultrasound |
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Authors: | Stoeckelhuber Beate M Wiesmann Martin Kreft Burkhard Stoeckelhuber Mechthild Weiss H Dieter Bergmann-Koester Claudia U |
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Affiliation: | Institut für Radiologie, Universit?tsklinikum Schleswig-Holstein, Campus Lübeck. stoeckel@medinf.mu-luebeck.de |
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Abstract: | PURPOSE: We evaluated different techniques of contrast-enhanced phase-inversion ultrasound to visualize renal perfusion. MATERIALS AND METHODS: Levovist contrast-enhanced phase-inversion ultrasound with different levels of mechanical index and frame rate was performed in 20 kidneys. Analysis using a software algorithm for time-resolved perfusion imaging was compared to single-image analysis performed by three independent radiologists. RESULTS: Optimal depiction of renal perfusion was achieved only by using a mechanical index which was high enough to destroy the microbubbles of the contrast agent (burst imaging) combined with a low frame rate (0.5 images/second). Renal cortex and medulla showed a homogeneous enhancement. Computer-assisted time-resolved perfusion analysis was applicable; it did not show additional Information to single-image analysis. CONCLUSION: Renal perfusion can be visualized using contrast-enhanced phase-inversion ultrasound. For depiction of bigger vessels, it is equal to B-mode ultrasound or Doppler mode techniques; however, it is superior for visualization of renal parenchymal perfusion. |
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