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西洋参叶中 20(s)-人参皂苷-Rh1,-Rh2和人参皂苷-Rh3的分离与鉴定
引用本文:丛登立 宋长春. 西洋参叶中 20(s)-人参皂苷-Rh1,-Rh2和人参皂苷-Rh3的分离与鉴定[J]. 中国药学杂志, 2000, 35(2): 82-84
作者姓名:丛登立 宋长春
作者单位::丛登立(长春 白求恩医科大学基础医学院 130021);宋长春(长春 白求恩医科大学基础医学院 130021)
摘    要: 目的:从西洋参叶中分离、鉴定20(s)-人参皂苷-Rh1,-Rh2和人参皂苷-Rh3,为了深入研究它们的生理活性,方法:以水提取,用多孔树脂吸附,再以体积分数为95%的乙醇洗脱,最后以硅胶柱层析分离。通过理化性质及IR,NMR光谱等方法测定,鉴定其结构。结果:共分得3个化合物,经鉴定后分别证明为20(s)-人参皂苷-Rh1,-Rh2,和人参皂苷-Rh3。结论:人参皂苷-Rh3为首次从西洋参叶中分离获得。

关 键 词:西洋参叶  20(s)-人参皂苷-Rh1  20(s)-人参皂苷-Rh2  人参皂苷-Rh3
收稿时间:1999-03-20;

Isolation andidentification of 20(s)-Ginsenoside-Rh1,-Rh2 and Ginsenoside-Rh3from the leaves of Panax quinquefolium
Cong DengliSong ChangchunXu Jingda. Isolation andidentification of 20(s)-Ginsenoside-Rh1,-Rh2 and Ginsenoside-Rh3from the leaves of Panax quinquefolium[J]. Chinese Pharmaceutical Journal, 2000, 35(2): 82-84
Authors:Cong DengliSong ChangchunXu Jingda
Affiliation:Cong Dengli(Cong DL);(Norman Bethune University of Medical Sciences,Changchun130021);Song Changchun(Song CC);(Norman Bethune University of Medical Sciences,Changchun130021);Xu Jingda(Xu JD);(Norman Bethune University of Medical Sciences,Changchun130021)
Abstract:OBJECTIVE20(s) Ginsenoside Rh-1, Rh-2 and Ginsenoside Rh-3 were isolated and identified from the leaves of Panax qulquefolium L.in order to thoroughly study their physiology activities. METHODS: They were extracted by water and absorbed by Macro reticular resins,then eluted with EtOH and isolated by silica Gel column chromatography the composition was identified by means of physiological and chemical properties IR,NMR respectively.RESULTS:Three chemical compounds were obtained.They were 20(s) Ginsenoside Rh-1, Rh-2 and Ginsenoside Rh-3. CONCLUSION:GinsenosideRh-3 was firstly isolated and obtained from the leaves of Panax quiquefolium L.
Keywords:leaves of Panax quiquefolium  20(s) Ginsenoside Rh-1  20(s) Ginsenoside Rh-2  Gensenoside Rh-3
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