脑动静脉畸形实验动物模型的建立

脑动静脉畸形是一种比较常见的严重威胁人们生命安全和生存质量的脑血管疾病，目前人们主要是通过尸体解剖以及CT、MRI等影像学的方法认识。近年来，学者们应用各种动物模型来研究脑动静脉畸形的血流动力学，病理生理学以及脑动静脉畸形栓塞材料的评估，栓塞后临床疗效评价，放射照射剂量对脑动静脉畸形的影响等。本文就脑动静脉畸形实验动物的常用种类，动物模型的建立方法以及动物模型的实际应用进行了综述。

Cerebral arteriovenous malformation construction of experimental animal model

Cerebral arteriovenous malfomation (AVM) is a kind of cerebral vascular disease that threatens people's life security and quality and people often realize it by the means of corpse anatomy and medical imaging including CT and MRI at present. In recent years, scholars have studied hemodynamics, pathophysiology, embolic materials, clinical embolic efficacy of the AVM and effect of radiation dosage using kinds of animal models. In this assay,the author reviewed kinds of experimental animals of the AVM, construction and practical use of animal model of the AVM.