Acute haemolytic anaemia in typhoid fever

Summary Two G-6-PD deficient children with typhoid fever complicated by acute haemolytic anaemia are reported. One of them had the rare complication of haemoglobinuria. The role of typhoid infection versus chloramphenicol treatment in causing haemolysis in G-6-PD deficiency is discussed. From the Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh.