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s—TIL对肝癌化疗栓塞后T淋巴细胞亚群的影响
引用本文:韦长元 刘剑仑. s—TIL对肝癌化疗栓塞后T淋巴细胞亚群的影响[J]. 实用癌症杂志, 2000, 15(4): 408-409
作者姓名:韦长元 刘剑仑
作者单位:广西医科大学肿瘤医院普瘤科
基金项目:广西壮族自治区科技厅资助! (No .9532 0 2 9)
摘    要:目的 观察原发性肝癌化疗栓塞畏加冷冻肝癌瘤苗刺激的肿瘤浸润淋巴细胞(s-TIL)治疗前后外周血T淋巴细胞受群的变化。方法 82例行化疗栓塞(TACE)后的肝癌患者分为s-TIL治疗组及对照组。2组分别于TACE治疗前及治疗后7天、14天、21天采外周静脉血检查T淋巴细胞亚群,2组进行比较。结果 治疗组CD3^+、CD4^+、CD8^+、CD4^+/CD3^+比值在14天左右即上升,与对照组比较有显

关 键 词:化疗栓塞 原发性肝癌 T细胞亚群 s-TIL

Effect of s-TIL on T Lymphocyte Subsets in Patients with PHC After TACE
WEI Chang yuan,LIU Jian lun,LI Ting,et al.. Effect of s-TIL on T Lymphocyte Subsets in Patients with PHC After TACE[J]. The Practical Journal of Cancer, 2000, 15(4): 408-409
Authors:WEI Chang yuan  LIU Jian lun  LI Ting  et al.
Affiliation:WEI Chang yuan,LIU Jian lun,LI Ting,et al. Cancer Hospital,Guangxi Medical University,Nannning,530021
Abstract:Objective To observe the changes of peripheral blood lymphocyte subsets in PHC patients treated by tumor infiltrating lymphocytes(TIL) stimulated with liver tumor cryovaccines after transcather arterial chemoembolization(TACE).Methods82 cases of PHC after TACE were divided into two groups,one was s TIL treatment group,the other was cortrol group.Peripheral blood T lymphocyte subsets of two groups were inspected and compared before and 7,14,21 days after treatment by TACE,respectively.Results The values of CD 3,CD 4,CD 8,CD 4/CD 8 in treatment group rose at about the 14 day after treatment,and it was significant compared with controls( P <0.05).Conclusion The application of s TIL to patients with PHC after TACE can enhance cellular immunity.
Keywords:Stimulated tumor lnfiltrating lymphocytes by tumor vaccines(s TIL)  Transcatheter arterial chemo embolization(TACE)  T lymphocyte subsets  Primary hepatocarcioma
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