| 基于数据挖掘分析甘草药对配伍应用规律 |
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| 引用本文： | 曹玉洁,唐于平,沈娟,谭亚杰,康安,段金廒. 基于数据挖掘分析甘草药对配伍应用规律[J]. 中草药, 2017, 48(21): 4552-4559 |
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| 作者姓名： | 曹玉洁 唐于平 沈娟 谭亚杰 康安 段金廒 |
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| 作者单位： | 南京中医药大学 江苏省中药资源产业化过程协同创新中心, 江苏省方剂高技术研究重点实验室, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学 江苏省中药资源产业化过程协同创新中心, 江苏省方剂高技术研究重点实验室, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学 江苏省中药资源产业化过程协同创新中心, 江苏省方剂高技术研究重点实验室, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学 江苏省中药资源产业化过程协同创新中心, 江苏省方剂高技术研究重点实验室, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学 江苏省中药资源产业化过程协同创新中心, 江苏省方剂高技术研究重点实验室, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023,南京中医药大学 江苏省中药资源产业化过程协同创新中心, 江苏省方剂高技术研究重点实验室, 中药资源产业化与方剂创新药物国家地方联合工程研究中心, 江苏 南京 210023 |
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| 基金项目： | 国家重点基础研究发展计划（“973计划”）（2011CB505300，2011CB505303） |
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| 摘 要： | 通过数据挖掘研究甘草在方剂中的配伍应用规律。应用计算机编程将中医方剂数据库中含有甘草的26 185首方剂信息读取为便于数据分析的形式,统计与甘草配伍较多的中药,对甘草与这些中药的配比,所治疾病科属,方剂功效及配比与科属、功效间的联系进行挖掘。通过数据挖掘发现甘草常与人参、当归、茯苓、芍药、姜、白术等药配伍应用,各药对配伍时常用比例多为1∶1,多用于内科疾病,常见方剂功效包括清热、止痛、化痰止咳平喘、温里、补虚、止呕、祛风化湿等。甘草的药性及功效是其配伍应用的基础,通过配伍应用起到增效减毒的目的,为甘草功效基础研究提供依据,为其临床应用提供参考。
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| 关 键 词： | 甘草 数据挖掘 配伍 功效 药对 |
| 收稿时间： | 2017-05-13 |
Analysis on compatibility and application of Glycyrrhizae Radix et Rhizoma and its herb pairs based on data mining method |
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| CAO Yu-jie,TANG Yu-ping,SHEN Juan,TAN Ya-jie,KANG An and DUAN Jin-ao. Analysis on compatibility and application of Glycyrrhizae Radix et Rhizoma and its herb pairs based on data mining method[J]. Chinese Traditional and Herbal Drugs, 2017, 48(21): 4552-4559 |
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| Authors: | CAO Yu-jie TANG Yu-ping SHEN Juan TAN Ya-jie KANG An DUAN Jin-ao |
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| Affiliation: | Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China,Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China,Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China,Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China,Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China and Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China |
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| Abstract: | |
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| Keywords: | Glycyrrhizae Radix et Rhizoma data mining compatibility efficacy herb pairs |
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