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低分子肝素治疗隐性冠心病30例疗效分析
引用本文:张绪洪,程彦华.低分子肝素治疗隐性冠心病30例疗效分析[J].中国煤炭工业医学杂志,2001,4(1):55-56.
作者姓名:张绪洪  程彦华
作者单位:1. 山东省立医院
2. 沂南县人民医院
摘    要:目的 探讨低分子肝素(栓复欣)治疗隐性冠心病的疗效。方法 将60例隐性冠心病患者随机分成2组(每组30例),观察组应用低分子肝素0.3ml(3200IUaXa),皮下注射,1/d,连用14d,对照组应用脉络宁20ml静滴,1/d,连用14d。观察用药前后动态心电图、血液粘稠度、红细胞聚集指数、血小板聚集率及血脂的变化等。结果 观察组全血粘稠度、血浆粘度、血小板聚集指数等显著降低,明显优于对照组,总有效率高于对照组(96.7%对63.3%)。结论 低分子肝素治疗隐性冠心病疗效显著。

关 键 词:隐性冠心病  低分子肝素  血粘度  药物治疗  疗效
文章编号:1007-9564(2001)01-0055-02
修稿时间:2000年4月24日

ANALYSIS OF THE EFFICACY OF 30 CASES OF LATENT CORONARY HEART DISEASE TREATED WITH LOWMOLECULAR WEIGHT HEPARIN
ZHANG Xuhong,Cheng Yianhua.ANALYSIS OF THE EFFICACY OF 30 CASES OF LATENT CORONARY HEART DISEASE TREATED WITH LOWMOLECULAR WEIGHT HEPARIN[J].Chinese Journal of Coal Industry Medicine,2001,4(1):55-56.
Authors:ZHANG Xuhong  Cheng Yianhua
Institution:Zhang Xuhong,Cheng Yianhua,Shandong Provincial Hospital,Jinan 250021
Abstract:Objective To study the efficacy of the low molecular weight heparin (parnaparin) fir the patients with latent coronary heart disease.Methods 60 cases were randomly divided into two groups with 30 cases of each group. The treatment group were given parnaparin 0.3ml (3200IuaXa) subcutaneously once a day for 14 days, while the control group were given Mailuo Ning 20ml intravenously once a day for 14 days. Before and after the treatment, observations were recorded about the changes of dynamic ECG, blood viscosity, red cell aggregation index, platelet aggregation rate and blood lipids etc.Results Blood viscosity, plasma viscosity and platelet aggregation rate etc in the treatment group were all obviously reduced, which was superior to the control group. The total effective rate in the treatment group was higher than that in the control group (96.7% vs 63.3%).Conclusion Low molecular weight heparin is remarkably effective for the treatment of latent coronary heart disease.
Keywords:Latent coronary heart disease  Low molecular weight heparin  Blood viscosity
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