| 静脉麻醉药与脑保护受体机制 |
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| 引用本文： | 王莉,金正均,杭燕南. 静脉麻醉药与脑保护受体机制[J]. 上海交通大学学报(医学版), 2004, 24(11): 978-980 |
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| 作者姓名： | 王莉 金正均 杭燕南 |
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| 作者单位： | [1]上海交通大学第六人民医院麻醉科,上海200233 [2]上海第二医科大学基础医学院药理教研室,上海200233 [3]上海第二医科大学仁济医院麻醉科,上海200233 |
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| 摘 要： | 兴奋毒性可能是造成神经元死亡的“最后公路”。已知静脉麻醉药，如非竞争性NMDA受体拮抗刹(氯胺酮)和GABA受体模拟剂(丙泊酚)有神经保护作用，该文就它们的神经保护作用的受体机制研究加以综述。
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| 关 键 词： | 静脉麻醉药 脑保护 受体机制 兴奋性氨基酸 |
| 文章编号： | 0258-5898(2004)11-0978-03 |
| 修稿时间： | 2004-04-11 |
Intravenous anesthetics and the receptor mechanism of neuroprotection |
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| WANG Li reviewer,JIN Zheng-jun,HANG Yan-nan revisers. Intravenous anesthetics and the receptor mechanism of neuroprotection[J]. Journal of Shanghai Jiaotong University:Medical Science, 2004, 24(11): 978-980 |
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| Authors: | WANG Li reviewer JIN Zheng-jun HANG Yan-nan revisers |
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| Abstract: | The excitotoxicity may be the last public way by which neurons were led to death. It has been shown that intravenous anesthetics, such as non-competitive NMDA antagonists (ketamine) or GABAmimetics (propofol) have neuroprotection. The receptor mechanism of neuroprotection by intravenous anesthesia was reviewed in this essay. |
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| Keywords: | excitatory amino acid NMDA brain protection intravenous anesthetics |
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