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Thymineless recombination in Saccharomyces cerevisiae is independent of the ability to undergo meiosis
Authors:Bernard A. Kunz  J. Gerard Little  Friederike Eckardt  Robert H. Haynes
Affiliation:(1) Biology Department, York University, M3J 1P3 Toronto, Ontario, Canada;(2) Gesellschaft für Strahlen- und Umweltforschung, D-8042 Neuherberg, Federal Republic of Germany;(3) Present address: Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, P.O. Box 12233, 27709 Research Triangle Park, NC, USA
Abstract:Summary Thymine nucleotide starvation is recombinagenic in Saccharomyces cerevisiae and induces formation of the lsquonuclear dense bodyrsquo, a structure characteristic of yeast cells in meiosis. Conceivably, thymineless recombination in yeast, presumed to be mitotic, might be meiotic in nature. We have tested this hypothesis and have found that thymineless recombination can be induced in strains incapable of meiotic exchange.
Keywords:Thymineless recombination  Meiosis
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