接触焦炉逸散物工人肺癌的流行病学研究

对１６个焦化厂１８５０６名男职工在原１１年回顾性队列研究基础上继续观察４年，使观察期延长到１５年（１９７１年１月１日－１９８５年１２月３１日），进一步研讨焦炉焦炉作业人群肺癌与焦炉逸散物的联系。研究结果表明：焦化厂的炼焦工作区人群肺癌是超量高发的癌症，超出量特别大，而肺癌在其它工作区均无显著超出。在炼焦工作区人群内，肺癌ＳＲＲ按非焦炉、炉侧、炉顶作业的顺序上升形成梯度：２．３８＜３．５５＜５．５６

EPIDEMIOLOGIC STUDY OF LUNG CANCER AMONG WORKERS EXPOSED TO COKE OVEN EMISSIONS

A continuous study on the basis of previous retrospective cohort mortality study was performed among workers in sixteen coking plants. The cohort consised of l8 506 males,and was studied over an overall observation period of 15 years,from l971 through l985,with an accumulation of 262699 person years. The standardized rate ratios(SRRs)from selected causes of death were calculated by comparing with the worker population in ten rough rolling mills.The lung cancer among the workers in coking work area showed a large excessive risk(SRR=3.82,P<0.01),but the lung cancer among the workers in other work areas did not show significant excess.In the coking work area the SRRs from lung cancer formed a gradient in order of nonoven,oven-side,and oven-top : 2.38>3.55>5.56.The gradient was consistent with concentration of benzene solubles in air of workplace at coke oven.A significant increasing excessive risk from lung cancer with increasing years since first exposure indicated also etiological association between the lung cancer and occupational exposure.