Real-time polymerase chain reaction and intraocular antibody production for the diagnosis of viral versus toxoplasmic infectious posterior uveitis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Real-time polymerase chain reaction and intraocular antibody production for the diagnosis of viral versus toxoplasmic infectious posterior uveitis

Authors:	Marie-Hélène Errera Pablo Goldschmidt Laurence Batellier Sandrine Degorge Emmanuel Héron Laurent Laroche José-Alain Sahel Mark Westcott Christine Chaumeil

Affiliation:	1.Service d’Ophtalmologie IV,Centre National d’Ophtalmologie des Quinze-Vingts,Paris,France;2.Laboratoire,Centre National d’Ophtalmologie des Quinze-Vingts,Paris,France;3.Service de Médecine Interne,Centre National d’Ophtalmologie des Quinze-Vingts,Paris,France;4.Service d’Ophtalmologie V,Centre National d’Ophtalmologie des Quinze-Vingts,Paris,France;5.Moorfields Eye Hospital,London,UK

Abstract:	Purpose The aim of this work was to determine the diagnostic performance of real-time polymerase chain reaction (RT-PCR) and to assess intraocular specific antibody secretion (Goldmann–Witmer coefficient) on samples from patients with signs of posterior uveitis presumably of infectious origin and to target the use of these two biologic tests in the diagnostic of Toxoplasma/viral Herpesviridae posterior uveitis by the consideration of clinical behavior and delay of intraocular sampling.

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