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血脂改变与川崎病冠状动脉病变的关系探讨
引用本文:阳明玉,张明,秦静庭,杨方源,王昕. 血脂改变与川崎病冠状动脉病变的关系探讨[J]. 中国全科医学, 2010, 13(2): 189-190
作者姓名:阳明玉  张明  秦静庭  杨方源  王昕
作者单位:桂林医学院附属医院儿科,广西桂林市,541001
基金项目:广西壮族自治区卫生厅计划课题(Z2009024)
摘    要:
目的探讨川崎病患儿血脂变化与冠状动脉病变的关系。方法采用氧化酶法和GPO—POD酶法分别测定46例川崎病患儿及30例健康儿童的血三酰甘油(TG)、胆固醇(TC)、低密度脂蛋白胆固醇(LDL—C)和高密度脂蛋白(HDL—C)。结果川崎病患儿急性期治疗前血TG、Tc及LDL—C增高,与正常对照组间差异有统计学意义(P〈0.05),血HDL—C降低,与正常对照组间差异有统计学意义(P〈0.05)。治疗后未并发冠脉病变组TG、TC及LDL—C均较治疗前降低,与治疗前相比差异有统计学意义(P〈0.05),HDL—C较治疗前升高,与治疗前相比差异有统计学意义(P〈0.01),与正常对照组相比差异无统计学意义(P〉0.05);而并发冠状动脉病变组血脂各指标与治疗前比较差异无统计学意义(P〉0.05)。结论血脂的动态测定可预测川崎病患儿并发冠状动脉病变的发生,有助于早期诊断。

关 键 词:血脂异常  黏膜皮肤淋巴结综合征  冠状动脉疾病

Relationship between Changes of Serum Lipid and Pathological Changes of Coronary Artery in Children with Kawasaki Disease
YANG+Ming-yu,ZHANG+Ming,QIN+Jing-ting,et+al. Relationship between Changes of Serum Lipid and Pathological Changes of Coronary Artery in Children with Kawasaki Disease[J]. Chinese General Practice, 2010, 13(2): 189-190
Authors:YANG+Ming-yu  ZHANG+Ming  QIN+Jing-ting  et+al
Affiliation:YANG+Ming-yu,ZHANG+Ming,QIN+Jing-ting,et+al.Department+of+Pediatrics,Affiliated+Hospital+of+Guilin+Medical+College,Guilin+541001,China
Abstract:
Objective To study the relationship between the changes of serum lipid and the pathological changes of coronary artery in children with Kawasaki disease(KD).Methods The levels of serum TG,TC,LDL-C and HDL-C were determined by methods of oxidase and GPO-POD in 46 KD and 30 healthy children.Results The levels of TG,TC,LDL-C increased and HDL-C decreased in KD children in acute phase before treatment,significantly different from those in control group(P<0.05).TG,TC,LDL-C decreased(P<0.05),and HDL-C increased(P...
Keywords:Dyslipidemias  Mucocutaneous lymph node syndrome  Coronary artery diseases  
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